Infectious disease models are important tools for understanding epidemiology and
supporting policy decisions for disease control. In the case of tuberculosis (TB), such models …

Background A large, double-blind, randomised, placebo-controlled trial of repeat BCG found
49% efficacy against leprosy but no protection against tuberculosis after 6–9 years' follow-up …

Background: Tuberculosis (TB) is caused by Mycobacterium tuberculosis complex (MTBC)
and remains a serious global public health threat, especially in resource-limited settings …

Understanding host and pathogen factors that influence tuberculosis (TB) transmission can
inform strategies to eliminate the spread of Mycobacterium tuberculosis (Mtb). Determining …

The occurrence of mixed infections of Mycobacterium tuberculosis is no longer disputed.
However, their frequency, and the impact they may have on our understanding of …

Urban slums in developing countries are experiencing the most rapid population growth of
any settlement type globally. Such growth of densely settled slums exerts a profound …

This paper summarises tuberculosis (TB) research over almost 30 years in Karonga District,
northern Malawi, an area typical of much of rural Africa. The dominant factor has been the …

Background While several studies have assessed the associations between biological
factors and tuberculosis (TB) transmission, our understanding of the associations between …

Rationale: HIV-associated tuberculosis remains a major health problem among the gold-
mining workforce in South Africa. We postulate that high levels of recent transmission …

The use of molecular tools for genotyping Mycobacterium tuberculosis isolates in
epidemiological surveys in order to identify clustered and orphan strains requires faster …