Advanced wound diagnostics: toward transforming wound care into precision medicine

MA Weigelt, HA Lev-Tov, M Tomic-Canic… - Advances in Wound …, 2022 - liebertpub.com
Significance: Nonhealing wounds are an ever-growing global pandemic, with mortality rates
and management costs exceeding many common cancers. Although our understanding of …

Dermatologic Manifestations of Mitochondrial Dysfunction: A Review of the Literature

N Natarelli, N Gahoonia, S Aflatooni, S Bhatia… - International Journal of …, 2024 - mdpi.com
Mitochondria are eukaryotic cellular organelles that function in energy metabolism, ROS
production, and programmed cell death. Cutaneous epithelial and hair follicle dermal papilla …

Photobiomodulation preserves mitochondrial redox state and is retinoprotective in a rodent model of retinitis pigmentosa

S Gopalakrishnan, S Mehrvar, S Maleki, H Schmitt… - Scientific Reports, 2020 - nature.com
Photobiomodulation (PBM) by far-red (FR) to near-infrared (NIR) light has been
demonstrated to restore the function of damaged mitochondria, increase the production of …

Patient-derived cancer organoid tracking with wide-field one-photon redox imaging to assess treatment response

DA Gil, D Deming, MC Skala - Journal of biomedical optics, 2021 - spiedigitallibrary.org
Significance: Accessible tools are needed for rapid, non-destructive imaging of patient-
derived cancer organoid (PCO) treatment response to accelerate drug discovery and …

Development of an endoscopic auto-fluorescent sensing device to aid in the detection of breast cancer and inform photodynamic therapy

B Gaitan, C Inglut, U Kanniyappan, HN Xu, EF Conant… - Metabolites, 2022 - mdpi.com
Breast cancer is the most diagnosed cancer type in women, with it being the second most
deadly cancer in terms of total yearly mortality. Due to the prevalence of this disease, better …

Application of 3D printing in the treatment of diabetic foot ulcers: current status and new insights

X Li, X Ai, B Wang, M Luo, A Miyamoto… - … in Bioengineering and …, 2024 - frontiersin.org
Background and Aims Diabetic foot ulcers (DFUs) are a serious complication of diabetes
mellitus (DM), affecting around 25% of individuals with DM. Primary treatment of a DFU …

[HTML][HTML] 670 nm photobiomodulation improves the mitochondrial redox state of diabetic wounds

S Mehrvar, S Mostaghimi, FH Foomani… - … Imaging in Medicine …, 2021 - ncbi.nlm.nih.gov
Background Photobiomodulation (PBM) by far-red (FR) to near-infrared (NIR) light has been
demonstrated to accelerate diabetic wound healing in preclinical and clinical studies …

Three-dimensional vascular and metabolic imaging using inverted autofluorescence

S Mehrvar, S Mostaghimi, AKS Camara… - Journal of …, 2021 - spiedigitallibrary.org
Significance: Three-dimensional (3D) vascular and metabolic imaging (VMI) of whole
organs in rodents provides critical and important (patho) physiological information in …

Optical metabolic imaging of mitochondrial dysfunction on HADH mutant newborn rat hearts

FH Foomani, JA Jarzembowski… - IEEE Journal of …, 2021 - ieeexplore.ieee.org
Background: Mitochondrial-oxidation of fatty acids is the primary energy source for the heart
and carried out by Hydroxy Acyl-CoA Dehydrogenase (HADH) encoded trifunctional protein …

Impact of wound dressing on mechanotransduction within tissues of chronic wounds

K McElvain, J Klister, A Ebben, S Gopalakrishnan… - Biomedicines, 2022 - mdpi.com
Chronic wounds are significant public health problems impacting the health-related quality
of individuals' lives (due to disability, decreased productivity, and loss of independence) and …