Mitochondrial dysfunction and its association with age-related disorders

I Somasundaram, SM Jain, M Blot-Chabaud… - Frontiers in …, 2024 - frontiersin.org
Aging is a complex process that features a functional decline in many organelles. Various
factors influence the aging process, such as chromosomal abnormalities, epigenetic …

[HTML][HTML] Ergothioneine and its prospects as an anti-ageing compound

Y Apparoo, CW Phan, UR Kuppusamy… - Experimental …, 2022 - Elsevier
Healthy ageing is a crucial process that needs to be highlighted as it affects the quality of
lifespan. An increase in oxidative stress along with ageing is the major factor related to the …

Understanding the unique microenvironment in the aging liver

Y Zhao, Y Yang, Q Li, J Li - Frontiers in Medicine, 2022 - frontiersin.org
In the past decades, many studies have focused on aging because of our pursuit of
longevity. With lifespans extended, the regenerative capacity of the liver gradually declines …

[PDF][PDF] Multiple roles of mitochondria in aging processes.

M Cedikova, P Pitule, M Kripnerova… - Physiological …, 2016 - researchgate.net
Aging is a multifactorial process influenced by genetic factors, nutrition, and lifestyle.
According to mitochondrial theory of aging, mitochondrial dysfunction is widely considered a …

Is 6-shogaol an effective phytochemical for patients with lower-risk myelodysplastic syndrome? a narrative review

SL Ooi, R Campbell, SC Pak… - Integrative Cancer …, 2021 - journals.sagepub.com
Myelodysplastic syndrome (MDS) evolves due to genomic instability, dysregulated signaling
pathways, and overproduction of inflammatory markers. Reactive oxygen species contribute …

Modulatory effect of ginger on skeletal malformations, cell cycle, apoptosis and structural changes in the liver of rat fetuses prenatally exposed to labetalol

HT El-Borm, MS Gobara, GM Badawy - Beni-Suef University Journal of …, 2023 - Springer
Background Drug-induced liver damage with clinical symptoms has been related to labetalol
in a number of instances. In addition to having a wide range of anti-inflammatory and …

[HTML][HTML] Zingiber officinale formulation reduces hepatic injury and weight gain in rats fed an unhealthy diet

DT Leal, GG Fontes, JKD Villa, RB Freitas… - Anais da Academia …, 2019 - SciELO Brasil
This study investigated the ability of formulation containing Zingiber officinale (ginger) to
reverse health changes promoted by unhealthy diet in Wistar rats. Five compounds from the …

Ultrastructural liver changes in the experimental thyrotoxicosis

NV Pasyechko, II Kuleshko, VM Kulchinska… - Polish Journal of …, 2017 - termedia.pl
In experimental thyrotoxicosis, on the background of microcirculatory disorders, significant
damage of plasmatic and intracellular organoid membranes of hepatocytes in the liver …

PROTECTIVE EFFECTS OF ALPHA LIPOIC ACID AGAINST LEADINDUCED OXIDATIVE STRESS AND DNA FRAGMENTATION TO TESTICULAR FUNCTION IN …

HF Murad, BN Al-Okaily - Biochemical & Cellular Archives, 2020 - search.ebscohost.com
This experiment was conducted to study the role of alpha lipoic acid (ALA) in alleviating
testicular oxidative stress and DNA fragmentation-induced by lead acetate (PbAc) in twenty …

Moringa oleifera extract could ameliorate aging-related structural and functional hepatic changes by regulating autophagy signaling pathway

HO Mohammed, RS Ramadan, A Fawzy… - Egyptian Journal of …, 2025 - ejh.journals.ekb.eg
hepatoprotective effect by inducing the antioxidant defense mechanism. Aim of the Study: To
evaluate aging-related impacts on the hepatic structure and function and the possible …