COVID-19: the inflammation link and the role of nutrition in potential mitigation

I Zabetakis, R Lordan, C Norton, A Tsoupras - Nutrients, 2020 - mdpi.com
The novel coronavirus disease (COVID-19) pandemic caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has engulfed the world, affecting more than 180 …

Platelet activation and prothrombotic mediators at the nexus of inflammation and atherosclerosis: Potential role of antiplatelet agents

R Lordan, A Tsoupras, I Zabetakis - Blood reviews, 2021 - Elsevier
Platelets are central to inflammation-related manifestations of cardiovascular diseases
(CVD) such as atherosclerosis. Platelet-activating factor (PAF), thrombin, thromboxane A 2 …

Forty years since the structural elucidation of platelet-activating factor (PAF): historical, current, and future research perspectives

R Lordan, A Tsoupras, I Zabetakis, CA Demopoulos - Molecules, 2019 - mdpi.com
In the late 1960s, Barbaro and Zvaifler described a substance that caused antigen induced
histamine release from rabbit platelets producing antibodies in passive cutaneous …

[HTML][HTML] Thrombosis and COVID-19: The Potential role of nutrition

A Tsoupras, R Lordan, I Zabetakis - Frontiers in Nutrition, 2020 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for the
coronavirus disease (COVID-19), is a contagion that has rapidly spread around the globe …

Cardiovascular diseases and marine oils: a focus on omega-3 polyunsaturated fatty acids and polar lipids

C Caffrey, A Leamy, E O'Sullivan, I Zabetakis, R Lordan… - Marine Drugs, 2023 - mdpi.com
Cardiovascular diseases (CVD) remain the leading cause of death across the globe, hence,
establishing strategies to counteract CVD are imperative to reduce mortality and the burden …

Antithrombotic properties of Spirulina extracts against platelet-activating factor and thrombin

P Koukouraki, A Tsoupras, G Sotiroudis… - Food Bioscience, 2020 - Elsevier
Spirulina (Arthrospira maxima) components have shown several health-benefits, including
immunomodulatory and anti-inflammatory properties. Even though a few studies have …

[HTML][HTML] The potential role of dietary platelet-activating factor inhibitors in cancer prevention and treatment

R Lordan, A Tsoupras, I Zabetakis - Advances in nutrition, 2019 - Elsevier
Cancer is the second leading cause of mortality worldwide. The role of unresolved
inflammation in cancer progression and metastasis is well established. Platelet-activating …

The association between dietary patterns and the novel inflammatory markers platelet-activating factor and lipoprotein-associated phospholipase A2: a systematic …

CJ English, HL Mayr, AE Lohning… - Nutrition …, 2022 - academic.oup.com
Context Atherosclerosis is a disease of chronic inflammation. Recent research has identified
2 novel inflammatory biomarkers: platelet-activating factor (PAF) and lipoprotein-associated …

In Vitro Antithrombotic Properties of Salmon (Salmo salar) Phospholipids in a Novel Food-Grade Extract

A Tsoupras, R Lordan, K Shiels, SK Saha… - Marine drugs, 2019 - mdpi.com
Marine and salmon polar lipids (PLs) extracted by conventional extractions with non-food-
grade solvents (CE-salmon-PLs) possess antithrombotic bioactivities against platelet …

The potential cardioprotective bioactive compounds in fermented alcoholic beverages: Mechanisms, challenges, and opportunities in beer and wine

S Hans, I Zabetakis, R Lordan - Nutrition Research, 2024 - Elsevier
Excessive alcohol consumption is generally regarded as highly detrimental to human health,
and it is implicated in the development of heart disease, stroke, and cancer. However, the …