[HTML][HTML] Recent preclinical and clinical progress in liposomal doxorubicin

K Aloss, P Hamar - Pharmaceutics, 2023 - mdpi.com
Doxorubicin (DOX) is a potent anti-cancer agent that has garnered great interest in research
due to its high efficacy despite dose-limiting toxicities. Several strategies have been …

Surface modification strategies in translocating nano-vesicles across different barriers and the role of bio-vesicles in improving anticancer therapy

P Tiwari, K Yadav, RP Shukla, S Gautam… - Journal of Controlled …, 2023 - Elsevier
Nanovesicles and bio-vesicles (BVs) have emerged as promising tools to achieve targeted
cancer therapy due to their ability to overcome many of the key challenges currently being …

Chitosan/carbon quantum dot/aptamer complex as a potential anticancer drug delivery system towards the release of 5-fluorouracil

HS Zavareh, M Pourmadadi, A Moradi… - International Journal of …, 2020 - Elsevier
Nowadays, nanotechnology contributes diminishing side effects rather than traditional
therapeutic methods like chemotherapy. Thus, designing a biocompatible specific targeted …

Aptamer-functionalized nanoparticles in targeted delivery and cancer therapy

Z Fu, J Xiang - International Journal of Molecular Sciences, 2020 - mdpi.com
Using nanoparticles to carry and delivery anticancer drugs holds much promise in cancer
therapy, but nanoparticles per se are lacking specificity. Active targeting, that is, using …

Aptamer-functionalized liposomes for targeted cancer therapy

SA Moosavian, P Kesharwani, V Singh… - … Nanocarriers for Cancer …, 2023 - Elsevier
Liposomes are among the most well-documented drug delivery systems in anticancer
therapy owing to their passive targeting capacities besides inherent biocompatibility and …

Redox-sensitive nanoscale drug delivery systems for cancer treatment

E Mirhadi, M Mashreghi, MF Maleki… - International journal of …, 2020 - Elsevier
Pharmaceutical nanotechnology introduces novel strategies in designing smart nanoscale
drug delivery systems (NDDSs) capable of responding to specific conditions. These smart …

Aptamers as versatile ligands for biomedical and pharmaceutical applications

B Guan, X Zhang - International journal of nanomedicine, 2020 - Taylor & Francis
Aptamers are a class of targeting ligands that bind exclusively to biomarkers of interest.
Aptamers have been identified as candidates for the construction of various smart systems …

Liposomes modified with bio-substances for cancer treatment

Y Li, H Cong, S Wang, B Yu, Y Shen - Biomaterials science, 2020 - pubs.rsc.org
In recent years, liposomes have been used in the field of biomedicine and have achieved
many significant results. Because of the unique characteristics of liposomes, there are many …

Challenges and pitfalls in the development of liposomal delivery systems for cancer therapy

SA Moosavian, V Bianconi, M Pirro… - Seminars in cancer …, 2021 - Elsevier
Despite considerable advances in the application of liposomal drug delivery systems in
cancer treatment, the clinical application of liposomal formulations has been limited by many …

Nanoencapsulation of aptamer-functionalized 5-Fluorouracil liposomes using alginate/chitosan complex as a novel targeting strategy for colon-specific drug delivery

M Khodarahmi, H Abbasi, M Kouchak… - Journal of Drug Delivery …, 2022 - Elsevier
Two important challenges in clinical application of 5-Fluorouracil (5-FU) in the treatment of
colon cancer are preventing the release or degradation of the drug in the stomach/small …