Loss of muscle proteins is a deleterious consequence of chronic kidney disease (CKD) that
causes a decrease in muscle strength and function, and can lead to a reduction in quality of …

Globally, diabetes is the leading cause of chronic kidney disease and end-stage renal
disease, which are major risk factors for cardiovascular disease and death. Despite this …

Aerobic exercise training and resistance exercise training are both well-known for their
ability to improve human health; especially in individuals with type 2 diabetes. However …

Although physical activity (PA) is a key element in the prevention and management of type 2
diabetes, many with this chronic disease do not become or remain regularly active. High …

The clear mechanism of moderate exercise training (Ex) in attenuating muscle loss remains
elusive in diabetes. We investigated the effects of moderate exercise training on diabetes …

Diabetes mellitus (DM) is a metabolic disease characterized by chronic hyperglycaemia,
with absolute insulin deficiency or insulin resistance as the main cause, and causes damage …

Given the manifold ways that depression impairs Darwinian fitness, the persistence in the
human genome of risk alleles for the disorder remains a much debated mystery …

Aging leads to functional changes in the hippocampus, and consequently induces cognitive
deficits, such as failure of memory. Neurogenesis in the hippocampal dentate gyrus …

Context Inflammation is increasingly recognized as contributing to the pathogenesis of major
depressive disorder (MDD), even in individuals who are otherwise medically healthy. Most …

Chronic kidney disease (CKD) is becoming a worldwide epidemic, driven largely by the
dramatic rise in the prevalence of diabetes and obesity. Novel targets and treatments for …