Four ounces can move a thousand pounds: the enormous value of nanomaterials in tumor immunotherapy

Z Chen, Z Yue, K Yang, C Shen… - Advanced …, 2023 - Wiley Online Library
The application of nanomaterials in healthcare has emerged as a promising strategy due to
their unique structural diversity, surface properties, and compositional diversity. In particular …

Loss of RPS27a expression regulates the cell cycle, apoptosis, and proliferation via the RPL11-MDM2-p53 pathway in lung adenocarcinoma cells

H Li, H Zhang, G Huang, Z Bing, D Xu, J Liu… - Journal of Experimental …, 2022 - Springer
Background Depletion of certain ribosomal proteins induces p53 activation, which is
mediated mainly by ribosomal protein L5 (RPL5) and/or ribosomal protein L11 (RPL11) …

Processing body (P-body) and its mediators in cancer

B Nsengimana, FA Khan, EE Ngowi, X Zhou… - Molecular and cellular …, 2022 - Springer
In recent years, processing bodies (P-bodies) formed by liquid–liquid phase separation,
have attracted growing scientific attention due to their involvement in numerous cellular …

[HTML][HTML] Honokiol inhibits interleukin-induced angiogenesis in the NSCLC microenvironment through the NF-κB signaling pathway

X Cheng, F Wang, Y Qiao, T Chen, L Fan… - Chemico-biological …, 2023 - Elsevier
Tumor angiogenesis, which may be affected by microenvironmental inflammation and
promotes tumor development and metastasis, is one of the key reasons contributing to …

Colocalization of MID1IP1 and c-Myc is critically involved in liver cancer growth via regulation of ribosomal protein L5 and L11 and CNOT2

JH Jung, HJ Lee, JH Kim, DY Sim, E Im, S Kim… - Cells, 2020 - mdpi.com
Though midline1 interacting protein 1 (MID1IP1) was known as one of the glucose-
responsive genes regulated by carbohydrate response element binding protein (ChREBP) …

Inhibition of CNOT2 induces apoptosis via MID1IP1 in colorectal cancer cells by activating p53

JH Jung, D Lee, HM Ko, HJ Jang - Biomolecules, 2021 - mdpi.com
CCR4-NOT transcription complex subunit 2 (CNOT2), a subunit of the CCR4-NOT complex,
has been described in cancer progression. The CNOT complex plays an important role in …

Prevalence, causes and impact of TP53-loss phenocopying events in human tumors

B Fito-Lopez, M Salvadores, MM Alvarez, F Supek - BMC biology, 2023 - Springer
Background TP53 is a master tumor suppressor gene, mutated in approximately half of all
human cancers. Given the many regulatory roles of the corresponding p53 protein, it is …

HAPLN3 inhibits apoptosis and promotes EMT of clear cell renal cell carcinoma via ERK and Bcl-2 signal pathways

Y Ding, S Xiong, X Chen, Q Pan, J Fan… - Journal of Cancer …, 2023 - Springer
Hyaluronan and proteoglycan link protein 3 (HAPLN3) is a member of the hyaluronan and
proteoglycan link protein family expressed in the extracellular matrix closely associated with …

ANXA9 facilitates S100A4 and promotes breast cancer progression through modulating STAT3 pathway

X Zhou, J Zhao, T Yan, D Ye, Y Wang, B Zhou… - Cell Death & …, 2024 - nature.com
Breast cancer has the highest global incidence and mortality rates among all cancer types.
Abnormal expression of the Annexin family has been observed in different malignant tumors …

Preparation and characterization of functionalized graphene oxide carrier for siRNA delivery

J Li, X Ge, C Cui, Y Zhang, Y Wang, X Wang… - International Journal of …, 2018 - mdpi.com
A successful siRNA delivery system is dependent on the development of a good siRNA
carrier. Graphene oxide (GO) has gained great attention as a promising nanocarrier in …