Protein-misfolding diseases, such as Alzheimer's disease, type 2 diabetes, Prion diseases,
and Parkinson's disease, are characterized by inflammatory reactions. In all these diseases …

Prion diseases are rare and neurodegenerative diseases that are characterized by the
misfolding and infectious spread of the prion protein in the brain, causing progressive and …

Prion diseases are neurodegenerative disorders characterized by the accumulation of a
disease-associated prion protein and apoptotic neuronal death. Previous studies indicated …

Magnetic iron oxide nanoparticles (IONPs) are frequently used for biomedical applications.
Although nanoparticles can enter the brain, little is known so far on the uptake of IONPs in …

Aims Present emerging world is emphasizing the implication of vitamin D deficiency
associated with development of inflammation and neurodegenerative disorder like …

Prion diseases are fatal neurodegenerative diseases characterized by spongiform change,
neuronal loss, and gliosis involving microglial activation in the central nervous system …

Abstract Tyrphostin 23 (T23) is a well-known inhibitor of protein tyrosine kinases. To
investigate potential acute effects of T23 on the viability and the glucose metabolism of brain …

Protein misfolding and accumulation of protein aggregates is a distinctive feature of most
neurodegenerative diseases. They lead to disruption of cellular homeostasis, loss of …

Prion diseases are lethal neurodegenerative diseases characterized by the misfolding of the
cellular prion protein, PrP C, into the infectious PrP Sc. PrP Sc accumulation in the brain …

Lewy body disorders are a group of neurodegenerative conditions characterized by the
pathological misfolding and aggregation of the abundant protein, α-synuclein. The most …