The development of neoplasia involves a complex and continuous interplay between
malignantly transformed cells and the tumour microenvironment (TME). Cancer …

Solid tumours comprise cancer cells that engage in continuous interactions with non-
malignant cells and with acellular components, forming the tumour microenvironment (TME) …

Synthetic extracellular matrix (ECM) mimics that can recapitulate the complex biochemical
and mechanical nature of native tissues are needed for advanced models of development …

The extracellular matrix (ECM) of solid tumors impacts the antitumor activities of CD8+ T and
natural killer (NK) cells in a variety of ways. Cell motility is restricted by the tumor ECM which …

Targeting the tumour immune microenvironment (TIME) by cancer immunotherapy has led to
improved patient outcomes. However, response to these treatments is heterogeneous and …

Immunoengineering is a rapidly evolving field that has been driving innovations in
manipulating immune system for new treatment tools and methods. The need for materials …

Inflammatory skin diseases, such as psoriasis and atopic dermatitis, pose significant health
challenges due to their long-lasting nature, potential for serious complications, and …

Disease-modifying drugs have transformed the treatment options for many systemic
autoimmune diseases. However, an evolving understanding of disease mechanisms, which …

Recent cumulative findings signify the adaptive immunity of materials as a key agenda in
tissue healing that can improve regenerative events and outcomes. Modulating immune …

The immune system plays a pivotal role in maintaining physiological homeostasis and
influencing disease processes. Dysregulated immune responses drive chronic inflammation …