Epidermal growth factor receptor: key to selective intracellular delivery
AA Rosenkranz, TA Slastnikova - Biochemistry (Moscow), 2020 - Springer
Epidermal growth factor receptor (EGFR) is an integral surface protein mediating cellular
response to a number of growth factors. Its overexpression and increased activation due to …
response to a number of growth factors. Its overexpression and increased activation due to …
[HTML][HTML] Removal of N-linked glycosylation enhances PD-L1 detection and predicts anti-PD-1/PD-L1 therapeutic efficacy
Reactivation of T cell immunity by PD-1/PD-L1 immune checkpoint blockade has been
shown to be a promising cancer therapeutic strategy. However, PD-L1 …
shown to be a promising cancer therapeutic strategy. However, PD-L1 …
[HTML][HTML] Progress on diagnostic and prognostic markers of pancreatic cancer
H Yang, W Li, L Ren, Y Yang, Y Zhang, B Ge… - Oncology …, 2023 - ncbi.nlm.nih.gov
Pancreatic cancer is a malignant disease characterized by low survival and high recurrence
rate, whose patients are mostly at the stage of locally advanced or metastatic disease when …
rate, whose patients are mostly at the stage of locally advanced or metastatic disease when …
Osteoclasts protect bone blood vessels against senescence through the angiogenin/plexin-B2 axis
Synthetic glucocorticoids (GCs), one of the most effective treatments for chronic inflammatory
and autoimmune conditions in children, have adverse effects on the growing skeleton. GCs …
and autoimmune conditions in children, have adverse effects on the growing skeleton. GCs …
Targeting ALK averts ribonuclease 1-induced immunosuppression and enhances antitumor immunity in hepatocellular carcinoma
C Liu, C Zhou, W Xia, Y Zhou, Y Qiu, J Weng… - Nature …, 2024 - nature.com
Tumor-secreted factors contribute to the development of a microenvironment that facilitates
the escape of cancer cells from immunotherapy. In this study, we conduct a retrospective …
the escape of cancer cells from immunotherapy. In this study, we conduct a retrospective …
Molecular and clinical characterization of ANG expression in gliomas and its association with tumor-related immune response
J Wang, A Shan, F Shi, Q Zheng - Frontiers in Medicine, 2023 - frontiersin.org
Background Angiogenin (ANG) has been widely reported as a crucial molecular regulator in
multiple malignancies. However, its role in gliomagenesis remains unclear. This study …
multiple malignancies. However, its role in gliomagenesis remains unclear. This study …
WFDC2 suppresses prostate cancer metastasis by modulating EGFR signaling inactivation
Y Xiong, L Yuan, S Chen, H Xu, T Peng, L Ju… - Cell death & …, 2020 - nature.com
WAP four-disulfide core domain 2 (WFDC2) is a small secretory protein that has been widely
studied in ovarian cancer. It has been proven that WFDC2 promotes proliferation and …
studied in ovarian cancer. It has been proven that WFDC2 promotes proliferation and …
[HTML][HTML] Catalytic activity-modulated etching of plasmonic gold nanorods enabled ultra-sensitive colorimetric strategy for Early-Stage cancer diagnosis
While the aberrant low expression of metallothioneins (MTs) in tissue has been recognized
as an effective indicator to spot the occurrence of early-stage malignant tumors, the ultra …
as an effective indicator to spot the occurrence of early-stage malignant tumors, the ultra …
The Epidermal Growth Factor Receptor Is a Relevant Host Factor in the Early Stages of The Zika Virus Life Cycle In Vitro
C Sabino, D Bender, ML Herrlein, E Hildt - Journal of virology, 2021 - Am Soc Microbiol
Zika virus (ZIKV) is a flavivirus that is well known for the epidemic in the Americas in 2015
and 2016 in which microcephaly in newborns and other neurological complications were …
and 2016 in which microcephaly in newborns and other neurological complications were …
Muc4 loss mitigates epidermal growth factor receptor activity essential for PDAC tumorigenesis
Abstract Mucin4 (MUC4) appears early during pancreatic intraepithelial neoplasia-1
(PanIN1), coinciding with the expression of epidermal growth factor receptor-1 (EGFR). The …
(PanIN1), coinciding with the expression of epidermal growth factor receptor-1 (EGFR). The …