Lyme disease (Lyme borreliosis) is a tick-borne, zoonosis of adults and children caused by
genospecies of the Borrelia burgdorferi sensu lato complex. The ailment, widespread …

Lyme disease Borrelia are obligately parasitic, tick-transmitted, invasive, persistent bacterial
pathogens that cause disease in humans and non-reservoir vertebrates primarily through …

Infectious agents can trigger autoimmune responses in a number of chronic inflammatory
diseases. Lyme arthritis, which is caused by the tick-transmitted spirochaete Borrelia …

BACKGROUND Autoimmune diseases often have strong genetic associations with specific
HLA-DR alleles. The synovial lesion in chronic inflammatory forms of arthritis shows marked …

Laminin (Ln) and collagen are multifunctional glycoproteins that play an important role in
cellular morphogenesis, cell signalling, tissue repair and cell migration. These proteins are …

Several pathogenic bacterial species intervene with the mammalian proteolytic plasminogen–
plasmin system. Recent developments have been made in understanding the structure and …

Lyme disease caused by Borrelia burgdorferi is the most common tick-borne disease in the
US and Europe. Unlike most bacteria, measurements of growth and viability of B. burgdorferi …

Is chronic illness in patients with Lyme disease caused by persistent infection? Three
decades of basic and clinical research have yet to produce a definitive answer to this …

Sunday, February 26, 2012 151a reservoirs. To disseminate within and between these
hosts, spirochetes must migrate through complex, polymeric environments such as the …

Borrelia burgdorferi, the tick-transmitted etiologic agent of Lyme borreliosis, can colonize
and persist in multiple tissue sites despite vigorous host immune responses. The …