The role of cardiac pericytes in health and disease: therapeutic targets for myocardial infarction

E Avolio, P Campagnolo, R Katare… - Nature Reviews …, 2024 - nature.com
Millions of cardiomyocytes die immediately after myocardial infarction, regardless of whether
the culprit coronary artery undergoes prompt revascularization. Residual ischaemia in the …

Inhibition of sodium-glucose cotransporter 2 suppresses renal stone formation

G Anan, T Hirose, D Kikuchi, C Takahashi… - Pharmacological …, 2022 - Elsevier
Background and aims Nephrolithiasis is a common renal disease with no effective
medication. Sodium-glucose cotransporter-2 (SGLT2) inhibitors, an anti-diabetic agent, have …

Coronary atherosclerosis and chemotherapy: From bench to bedside

F Zhou, X Zhu, Y Liu, Y Sun, Y Zhang… - Frontiers in …, 2023 - frontiersin.org
Cardiovascular disease, particularly coronary artery disease, is the leading cause of death
in humans worldwide. Coronary heart disease caused by chemotherapy affects the …

Pericyte detachment and renal congestion involve interstitial injury and fibrosis in Dahl salt-sensitive rats and humans with heart failure

H Ito, T Hirose, S Sato, C Takahashi, R Ishikawa… - Hypertension …, 2023 - nature.com
Congestive heart failure produces fluid volume overload, central and renal venous pressure
elevation, and consequently renal congestion, which results in worsening renal function …

Sodium glucose cotransporter 2 inhibitor suppresses renal injury in rats with renal congestion

A Endo, T Hirose, S Sato, H Ito, C Takahashi… - Hypertension …, 2024 - nature.com
Renal congestion is an issue of cardiorenal syndrome in patients with heart failure. Recent
clinical and basic studies suggest a renoprotective potential of sodium–glucose …

Cardiorenal syndrome in Heart Failure with Preserved Ejection Fraction: Insights into pathophysiology and recent advances

H Khandait, SS Sodhi, N Khandekar… - Cardiorenal Medicine, 2025 - karger.com
Background: Cardiorenal syndrome (CRS) refers to the bidirectional interactions between
the acutely or chronically dysfunctioning heart and kidney that lead to poor outcomes. Due to …

SGLT2 inhibitors in the treatment of type 2 cardiorenal syndrome: Focus on renal tubules

Y Wang, X Mao, S Shi, X Xu, J Lv, B Zhang… - Frontiers in …, 2023 - frontiersin.org
The pathogenesis of type 2 cardiorenal syndrome (CRS) is mostly associated with reduced
cardiac output, increased central venous pressure (CVP), activation of the renin-angiotensin …

Renal venous hypertension to the regulation of pressure natriuresis in heart failure

T Mori - Hypertension Research, 2024 - nature.com
Pressure natriuresis relationship is well established by Author Guyton and his associates [1].
This mechanism play an important role in the blood pressure and body fluid control …

[PDF][PDF] The role of cardiac pericytes in health and disease: therapeutic targets for myocardial infarction. Nature Reviews Cardiology, 21 (2), 106-118. Advance online …

E Avolio, P Campagnolo, RG Katare, PR Madeddu - research-information.bris.ac.uk
Avolio, E., Campagnolo, P., Katare, RG, & Madeddu, PR (2023). The role of cardiac pericytes in
health and disease: the Page 1 Avolio, E., Campagnolo, P., Katare, RG, & Madeddu, PR (2023) …