Microemulsions, as thermodynamically stable mixtures of oil, water, and surfactant, are
known and have been studied for more than 70 years. However, even today there are still …

Milk thistle (Silybum marianum) is a medicinal plant that has been used for thousands of
years as a remedy for a variety of ailments. The main component of S. marianum fruit extract …

Drugs with low water solubility are predisposed to low and variable oral bioavailability and,
therefore, to variability in clinical response. Despite significant efforts to “design in” …

Lipid based formulations (LBF) provide well proven opportunities to enhance the oral
absorption of drugs and drug candidates that sit close to, or beyond, the boundaries of …

Lipid nanoparticles based on solid matrix have emerged as potential drug carriers to
improve gastrointestinal (GI) absorption and oral bioavailability of several drugs, especially …

Microemulsions are clear, stable, isotropic mixtures of oil, water and surfactant, frequently in
combination with a cosurfactant. These systems are currently of interest to the …

The oral delivery of hydrophobic drugs presents a major challenge because of the low
aqueous solubility of such compounds. Self-emulsifying drug delivery systems (SEDDS) …

'Lipid'formulations for oral administration of drugs generally consist of a drug dissolved in a
blend of two or more excipients, which may be triglyceride oils, partial glycerides, surfactants …

Oral lipid-based drug delivery systems may include a broad range of oils, surfactants, and
cosolvents. This diversity makes comparison of lipid-based formulations difficult. Although …

The objective of our investigation was to design a thermodynamically stable and dilutable
nanoemulsion formulation of Ramipril, with minimum surfactant concentration that could …