The recent epidemics of metabolic diseases, obesity, type 2 diabetes (T2D), liver lipid
disorders and metabolic syndrome have largely been attributed to genetic background and …

The importance of dopamine in central nervous system function is well known, but its effects
on glucose homeostasis and pancreatic β cell function are beginning to be unraveled …

The Drd2 gene, encoding the dopamine D 2 receptor (D2R), was recently indicated as a
potential target in the etiology of lowered sociability (ie, social withdrawal), a symptom of …

Male house mice excrete large amounts of protein in their urinary scent marks, mainly
composed of Major Urinary Proteins (MUPs), and these lipocalins function as pheromones …

Proteostatic regulation of tyrosine hydroxylase (TH), the rate‐limiting enzyme in dopamine
biosynthesis, is crucial for maintaining proper brain neurotransmitter homeostasis. Variants …

We have previously shown that male mice living in groups of 12 males establish and
maintain stable linear social hierarchies with each individual having a defined social rank …

Background The association of high serum prolactin and increased body weight is positive
but controversial, therefore we hypothesized that additional factors such as diets and the …

Catatonia is a psychiatric disorder, which subsumes a plethora of affective, motor and
behavioral symptoms. In the last two decades, the number of behavioral and neuroimaging …

Motor execution and planning are tightly regulated by dopamine D1 and D2 receptors
present in basal ganglia circuits. Although stimulation of D1 receptors is known to enhance …

Growth hormone (GH) acts in several hypothalamic neuronal populations to modulate
metabolism and the autoregulation of GH secretion via negative-feedback loops. However …