Allenes are a class of unique compounds with two π-orbitals perpendicular to each other.
The first synthesis can be traced back to 1887. 1 They also exist in many natural products …

The cyclopentenone unit is a very powerful synthon for the synthesis of a variety of bioactive
target molecules. This is due to the broad diversity of chemical modifications available for …

There are still some synthetic chemists who hesitate to use metal-mediated or-catalysed
reactions. The Pauson–Khand reaction (PKR) is a powerful transformation that has now …

Reaction of benzyl (2, 2-diphenyl-4, 5-hexadienyl) carbamate (4) with a catalytic 1: 1 mixture
of Au [P (t-Bu) 2 (o-biphenyl)] Cl (2) and AgOTf (5 mol%) in dioxane at 25° C for 45 min led to …

The present review is focused on the application of computational/theoretical methods to the
wide and rich chemistry of allenes. Special emphasis is made on the interplay and synergy …

The use of organometallic reagents for the synthesis of allenes is highly developed, and
several fundamentally different methods are now well established. These include transition …

The dynamic kinetic asymmetric allylic alkylations of racemic allene acetates has been
developed with the DACH− phenyl Trost ligand 2 to give general access to allenes with high …

Substrates, bearing axial chirality, can cyclize intra-or inter-molecularly with concomitant
transfer of axial-to-central chirality to produce at least one stereocenter. In order to satisfy a …

The [2+ 2+ 1] cyclization of an alkyne, an alkene and carbon monoxide, ie, the Pauson–
Khand reaction, is one of the most powerful tools for constructing a five-membered ring. In …

The unique structural architecture of the orthogonal cumulative π-system in allenes has
garnered the attention of synthetic chemists for over a century. 1 From a general reactivity …