Vasopressin V1a and V1b receptors: from molecules to physiological systems

T Koshimizu, K Nakamura, N Egashira… - Physiological …, 2012 - journals.physiology.org
The neurohypophysial hormone arginine vasopressin (AVP) is essential for a wide range of
physiological functions, including water reabsorption, cardiovascular homeostasis, hormone …

Oxytocin and vasopressin agonists and antagonists as research tools and potential therapeutics

M Manning, A Misicka, A Olma… - Journal of …, 2012 - Wiley Online Library
We recently reviewed the status of peptide and nonpeptide agonists and antagonists for the
V1a, V1b and V2 receptors for arginine vasopressin (AVP) and the oxytocin receptor for …

GPCR-G protein-β-arrestin super-complex mediates sustained G protein signaling

ARB Thomsen, B Plouffe, TJ Cahill, AK Shukla… - Cell, 2016 - cell.com
Classically, G protein-coupled receptor (GPCR) stimulation promotes G protein signaling at
the plasma membrane, followed by rapid β-arrestin-mediated desensitization and receptor …

Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants

JP Morello, A Salahpour, A Laperrière… - The Journal of …, 2000 - Am Soc Clin Investig
Over 150 mutations within the coding sequence of the V2 vasopressin receptor (V2R) gene
are known to cause nephrogenic diabetes insipidus (NDI). A large number of these mutant …

Central nervous system effects of the neurohypophyseal hormones and related peptides

D de Wied, M Diamant, M Fodor - Frontiers in neuroendocrinology, 1993 - Elsevier
This review of the CNS effects of the neurohypophyseal hormones and related
neuropeptides discusses recent data illustrating the significance of these principles in brain …

Localization and pharmacological characterization of high affinity binding sites for vasopressin and oxytocin in the rat brain by light microscopic autoradiography

E Tribollet, C Barberis, S Jard, M Dubois-Dauphin… - Brain research, 1988 - Elsevier
Sites which bind tritiated vasopressin (AVP) with high affinity were detected in the brain of
male, adult rats, by light microscopic autoradiography. Their anatomical localization differed …

Peptide and non-peptide agonists and antagonists for the vasopressin and oxytocin V1a, V1b, V2 and OT receptors: research tools and potential therapeutic agents

M Manning, S Stoev, B Chini, T Durroux… - Progress in brain …, 2008 - Elsevier
Oxytocin (OT) and vasopressin (AVP) mediate their biological actions by acting on four
known receptors: The OT (uterine) and the AVP V 1a (vasopressor), V 1b (pituitary), V 2 …

Vasopressin and the regulation of hypothalamic-pituitary-adrenal axis function: implications for the pathophysiology of depression

LV Scott, TG Dinan - Life sciences, 1998 - Elsevier
The role of arginine vasopressin (AVP/VP) in the control of adrenocorticotropic hormone
(ACTH) secretion is explored, and in particular, its involvement in various stress response …

Extrapituitary expression of the rat V1b vasopressin receptor gene.

SJ Lolait, AM O'Carroll, LC Mahan… - Proceedings of the …, 1995 - National Acad Sciences
[Arg8] vasopressin (AVP) stimulates adrenocorticotropic hormone release from the anterior
pituitary by acting on the V1b AVP receptor. This receptor can be distinguished from the …

The vasopressin V1b receptor critically regulates hypothalamic-pituitary-adrenal axis activity under both stress and resting conditions

A Tanoue, S Ito, K Honda, S Oshikawa… - The Journal of …, 2004 - Am Soc Clin Investig
The neurohypophyseal peptide [Arg8]-vasopressin (AVP) exerts major physiological actions
through three distinct receptor isoforms designated V1a, V1b, and V2. Among these three …