Ganoderma lucidum: A potential pleiotropic approach of ganoderic acids in health reinforcement and factors influencing their production

MF Ahmad, S Wahab, FA Ahmad, SA Ashraf… - Fungal Biology …, 2022 - Elsevier
Ganoderma lucidum (G. lucidum) main attractive pharmacological characteristics are
antitumor and immunomodulatory activities which are chiefly associated with its two …

Shedding light on the mechanisms underlying the environmental regulation of secondary metabolite ganoderic acid in Ganoderma lucidum using physiological and …

A Ren, L Shi, J Zhu, H Yu, A Jiang, H Zheng… - Fungal genetics and …, 2019 - Elsevier
The secondary metabolites of fungi are often produced at very low concentrations, and until
recently the regulatory mechanisms of secondary metabolite biosynthesis have been …

Functions of the nicotinamide adenine dinucleotide phosphate oxidase family in Ganoderma lucidum: an essential role in ganoderic acid biosynthesis regulation …

D Mu, C Li, X Zhang, X Li, L Shi… - Environmental …, 2014 - Wiley Online Library
G anoderma lucidum has drawn worldwide interest with regard to its secondary metabolism
and pharmaceutical activity. However, the development of such research has been limited …

Hydrogen‐rich water regulates effects of ROS balance on morphology, growth and secondary metabolism via glutathione peroxidase in Ganoderma lucidum

A Ren, R Liu, ZG Miao, X Zhang, PF Cao… - Environmental …, 2017 - Wiley Online Library
Ganoderma lucidum is one of the most important medicinal fungi, but the lack of basic study
on the fungus has hindered the further development of its value. To investigate the roles of …

[HTML][HTML] Heat stress-induced reactive oxygen species participate in the regulation of HSP expression, hyphal branching and ganoderic acid biosynthesis in …

R Liu, X Zhang, A Ren, DK Shi, L Shi, J Zhu… - Microbiological …, 2018 - Elsevier
Heat stress (HS) is an important environmental factor that affects the growth and metabolism
of edible fungi, but the molecular mechanism of the heat stress response (HSR) remains …

A Novel Approach to Enhancing Ganoderic Acid Production by Ganoderma lucidum Using Apoptosis Induction

BJ You, MH Lee, N Tien, MS Lee, HC Hsieh, LH Tseng… - PloS one, 2013 - journals.plos.org
Ganoderma lucidum is one of most widely used herbal medicine and functional food in Asia,
and ganoderic acids (GAs) are its active ingredients. Regulation of GA biosynthesis and …

Biosynthesis, Gene Expression, and Pharmacological Properties of Triterpenoids of Ganoderma Species (Agaricomycetes): A Review

LT Angulo-Sanchez, D López-Peña… - … Journal of Medicinal …, 2022 - dl.begellhouse.com
For more than 6 millennia, Ganoderma species have been used in traditional Asian
medicine due to their health benefits. Ganoderma synthesizes several compounds with …

The regulation of methyl jasmonate on hyphal branching and GA biosynthesis in Ganoderma lucidum partly via ROS generated by NADPH oxidase

L Shi, L Gong, X Zhang, A Ren, T Gao… - Fungal Genetics and …, 2015 - Elsevier
Ganoderma lucidum is one of the best known medicinal basidiomycetes because it
produces many pharmacologically active compounds, and methyl jasmonate (MeJA) was …

The mitogen-activated protein kinase GlSlt2 regulates fungal growth, fruiting body development, cell wall integrity, oxidative stress and ganoderic acid biosynthesis in …

G Zhang, Z Sun, A Ren, L Shi, D Shi, X Li… - Fungal Genetics and …, 2017 - Elsevier
The mitogen-activated protein kinases (MAPKs) are crucial signaling instruments in
eukaryotes that play key roles in regulating fungal growth, development, and secondary …

Transcriptomic responses involved in enhanced production of hypocrellin A by addition of Triton X-100 in submerged cultures of Shiraia bambusicola

XY Lei, MY Zhang, YJ Ma… - Journal of Industrial …, 2017 - academic.oup.com
The addition of surfactant is a useful strategy to enhance the product yield in submerged
fermentation process. In this study, we sought to explore the mechanism for the elicitation of …