The hypermobile type of Ehlers–Danlos syndrome (hEDS) is likely the most common
hereditary disorder of connective tissue. It has been described largely in those with …

Postural tachycardia syndrome (POTS) is one of the most common forms of chronic
orthostatic intolerance. In addition to orthostatic symptoms, many POTS patients report …

Background: There have been previous reports of enhanced sympathoexcitation in autism
spectrum disorder (ASD). However, there has been no formal investigation of autonomic …

Neurology and connective tissue are intimately interdependent systems and are critical in
regulating many of the body's systems. Unlocking their multifaceted relationship can …

Abstract Background The Ehlers-Danlos syndromes (EDS) are rare connective tissue
disorders consisting of 13 subtypes with overlapping features including joint hypermobility …

Ehlers–Danlos syndromes (EDS) are a heterogeneous group of hereditary connective tissue
disorders characterized by joint hypermobility, widespread musculoskeletal pain and tissue …

Predictive coding models, such as the 'free-energy principle'(FEP), have recently been
discussed in relation to how interoceptive (afferent visceral feedback) signals update …

We have suggested that reduced food intake increases the risk for anorexia nervosa by
engaging mesolimbic dopamine neurons, thereby initially rewarding dieting. Recent fMRI …

Dysautonomia (autonomic dysfunction) occurs in the Ehlers–Danlos syndromes (EDS) and
hypermobility spectrum disorders (HSD). Symptoms include palpitations, dizziness …

Cardiac vagal control (CVC) reflects the activity of the vagus nerve regulating cardiac
functioning. CVC can be inferred via heart rate variability measurement, and it has been …