[HTML][HTML] Network pharmacology reveals that Berberine may function against Alzheimer's disease via the AKT signaling pathway

W Wei, J Yao, T Zhang, J Wen, Z Zhang… - Frontiers in …, 2023 - frontiersin.org
Objective To investigate the mechanism underlying the effects of berberine (BBR) in the
treatment of Alzheimer's disease (AD). Methods 3× Tg AD mice were treated with BBR for 3 …

Network pharmacology‒based analysis of marine cyanobacteria derived bioactive compounds for application to Alzheimer's disease

R Xie, F Chen, Y Ma, W Hu, Q Zheng, J Cao… - Frontiers in …, 2023 - frontiersin.org
In recent years, the Alzheimer's disease (AD) epidemic has become one of the largest global
healthcare crises. Besides, the available systemic therapies for AD are still inadequate. Due …

[HTML][HTML] Network-based identification and mechanism exploration of active ingredients against Alzheimer's disease via targeting endoplasmic reticulum stress from …

Z Dai, T Hu, J Wei, X Wang, C Cai, Y Gu, Y Hu… - Computational and …, 2024 - Elsevier
Alzheimer's disease is a neurodegenerative disease that leads to dementia and poses a
serious threat to the health of the elderly. Traditional Chinese medicine (TCM) presents as a …

CircPAN3/miR-221/PTEN axis and apoptosis in myocardial Infarction: Quercetin's regulatory effects

MM Farazi, F Rostamzadeh, S Jafarinejad-Farsangi… - Gene, 2024 - Elsevier
The circular RNA/microRNA/mRNA axis is a new layer of non-coding RNA-based regulatory
gene expression networks upstream of numerous cell signaling pathways. Circular RNA …