The sequence of microbial genomes made all potential antigens of each pathogen available
for vaccine development. This increased by orders of magnitude potential vaccine targets in …

In March and early April 2009 a new swine-origin influenza virus (S-OIV), A (H1N1),
emerged in Mexico and the USA. The virus quickly spread worldwide through human-to …

Protein therapeutics hold a prominent and rapidly expanding place among medicinal
products. Purified blood products, recombinant cytokines, growth factors, enzyme …

Epidemiological studies regarding many successful vaccines suggest that vaccination may
lead to a reduction in child mortality and morbidity worldwide, on a grander scale than is …

Influenza A viruses belong to the best studied viruses, however no effective prevention
against influenza infection has been developed. The emerging of still new escape variants …

Vaccine informatics is an emerging research area that focuses on development and
applications of bioinformatics methods that can be used to facilitate every aspect of the …

Computational vaccine design, also known as computational vaccinology, encompasses
epitope mapping, antigen selection and immunogen design using computational tools. The …

A reverse vaccinology system, Vaxign, was used to identify and select a subset of five
African Swine Fever (ASF) antigens that were successfully purified from human embryonic …

Zika virus (ZIKV) is a flavivirus primarily transmitted by Aedes species mosquitoes, first
discovered in Africa in 1947, that disseminated through Southeast Asia and the Pacific …

Genetic mutation and reassortment of influenza virus gene segments, in particular those of
hemagglutinin (HA) and neuraminidase (NA), that lead to antigenic drift and shift are the …