Synthesis of side-chain modified polypeptides

TJ Deming - Chemical reviews, 2016 - ACS Publications
Proteins have long fascinated scientists since their complex sequences and diversity of
chemical functionality can lead to structurally defined folded chains with highly specific …

Polypeptide organic radical batteries

TP Nguyen, AD Easley, N Kang, S Khan, SM Lim… - Nature, 2021 - nature.com
In only a few decades, lithium-ion batteries have revolutionized technologies, enabling the
proliferation of portable devices and electric vehicles, with substantial benefits for society …

Construction of Smart DNA‐Based Drug Delivery Systems for Cancer Therapy

C Li, M Wang, PF Li, J Sheng, Q Fu - Small, 2024 - Wiley Online Library
Due to the disadvantages of poor targeting, slow action, and low effectiveness of current
commonly used cancer treatments, including surgery, chemotherapy, and radiotherapy …

Intertwining DNA-RNA nanocapsules loaded with tumor neoantigens as synergistic nanovaccines for cancer immunotherapy

G Zhu, L Mei, HD Vishwasrao, O Jacobson… - Nature …, 2017 - nature.com
Nanomedicines that co-deliver DNA, RNA, and peptide therapeutics are highly desirable yet
remain underdeveloped for cancer theranostics. Herein, we report self-assembled …

Preparation and in Vitro Antimicrobial Activity of Silver-Bearing Degradable Polymeric Nanoparticles of Polyphosphoester-block-Poly(l-lactide)

YH Lim, KM Tiemann, GS Heo, PO Wagers… - ACS …, 2015 - ACS Publications
The development of well-defined polymeric nanoparticles (NPs) as delivery carriers for
antimicrobials targeting human infectious diseases requires rational design of the polymer …

Polypeptide-based systems: From synthesis to application in drug delivery

M Stepanova, A Nikiforov, T Tennikova… - Pharmaceutics, 2023 - mdpi.com
Synthetic polypeptides are biocompatible and biodegradable macromolecules whose
composition and architecture can vary over a wide range. Their unique ability to form …

DNA nanodevice-based drug delivery systems

C Guan, X Zhu, C Feng - Biomolecules, 2021 - mdpi.com
DNA, a natural biological material, has become an ideal choice for biomedical applications,
mainly owing to its good biocompatibility, ease of synthesis, modifiability, and especially …

Functional sugar-based polymers and nanostructures comprised of degradable poly (D-glucose carbonate) s

L Su, S Khan, J Fan, YN Lin, H Wang… - Polymer …, 2017 - pubs.rsc.org
Fundamental synthetic methodology was advanced to allow for the preparation of a reactive
glucose-based block copolycarbonate, which was conveniently transformed into a series of …

Stimuli‐Triggered Sol–Gel Transitions of Polypeptides Derived from α‐Amino Acid N‐Carboxyanhydride (NCA) Polymerizations

X He, J Fan, KL Wooley - Chemistry–An Asian Journal, 2016 - Wiley Online Library
The past decade has witnessed significantly increased interest in the development of smart
polypeptide‐based organo‐and hydrogel systems with stimuli responsiveness, especially …

Of thiols and disulfides: Methods for chemoselective formation of asymmetric disulfides in synthetic peptides and polymers

O Schäfer, M Barz - Chemistry–A European Journal, 2018 - Wiley Online Library
In protein or peptide chemistry, thiols are frequently chosen as a chemical entity for
chemoselective modification reactions. Although it is a well‐established methodology to …