Past, current, and potential treatments for cryptosporidiosis in humans and farm animals: A comprehensive review

SM Khan, WH Witola - Frontiers in cellular and infection microbiology, 2023 - frontiersin.org
The intracellular protozoan parasite of the genus Cryptosporidium is among the leading
causes of waterborne diarrheal disease outbreaks throughout the world. The parasite is …

Cryptosporidiosis: from prevention to treatment, a narrative review

YA Helmy, HM Hafez - Microorganisms, 2022 - mdpi.com
Cryptosporidiosis is a water-and food-borne zoonotic disease caused by the protozoon
parasite of the genus Cryptosporidium. C. hominis and C. parvum are the main two species …

[HTML][HTML] Downregulation of nutrition sensor GCN2 in macrophages contributes to poor wound healing in diabetes

Y Hou, D Wei, Z Zhang, T Lei, S Li, J Bao, H Guo, L Tan… - Cell Reports, 2024 - cell.com
Poor skin wound healing, which is common in patients with diabetes, is related to
imbalanced macrophage polarization. Here, we find that nutrition sensor GCN2 (general …

Prospects of halofuginone as an antiprotozoal drug scaffold

J Gill, A Sharma - Drug discovery today, 2022 - Elsevier
Highlights•The global prevalence of parasitic protozoan diseases remains a significant
public health challenge.•Halofuginone, a plant-derived compound, has beneficial roles in …

Cross-Border Investigations on the Prevalence and Transmission Dynamics of Cryptosporidium Species in Dairy Cattle Farms in Western Mainland Europe

P Pinto, CA Ribeiro, S Hoque, O Hammouma… - Microorganisms, 2021 - mdpi.com
Cryptosporidium is an apicomplexan parasitic protist, which infects a wide range of hosts,
causing cryptosporidiosis disease. In farms, the incidence of this disease is high in animals …

Host innate immune responses and microbiome profile of neonatal calves challenged with Cryptosporidium parvum and the effect of bovine colostrum …

L Gamsjäger, KM Cirone, S Schluessel… - Frontiers in cellular …, 2023 - frontiersin.org
Introduction Calves are highly susceptible to gastrointestinal infection with Cryptosporidium
parvum (C. parvum), which can result in watery diarrhea and eventually death or impaired …

Advances in therapeutic and vaccine targets for Cryptosporidium: Challenges and possible mitigation strategies

SU Rahman, R Mi, S Zhou, H Gong, M Ullah, Y Huang… - Acta Tropica, 2022 - Elsevier
Cryptosporidium is known to be the second most common diarrheal pathogen in children,
causing potentially fatal diarrhea and associated with long-term growth stunting and …

A fractional perspective on the transmission dynamics of a parasitic infection, considering the impact of both strong and weak immunity

TQ Tang, R Jan, Z Shah, N Vrinceanu, C Tanasescu… - Plos one, 2024 - journals.plos.org
Infectious disease cryptosporidiosis is caused by the cryptosporidium parasite, a type of
parasitic organism. It is spread through the ingestion of contaminated water, food, or fecal …

[PDF][PDF] Cryptosporidiosis: A Foodborne Zoonotic Disease of Farm Animals and Humans.

K Javed, KA Alkheraije - Pakistan Veterinary Journal, 2023 - pvj.com.pk
Globally, the major concerns that are related to morbidity and high rates of death in the
human community are foodborne illnesses. Cryptosporidium is a significant foodborne …

Huang Bai Jian Pi decoction alleviates diarrhea and represses inflammatory injury via PI3K/Akt/NF-κB pathway: In vivo and in vitro studies

Z Yan, K Zhang, K Zhang, G Wang, L Wang… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Huang Bai Jian Pi (HBJP) decoction, a Chinese
herbal formula based on the Pulsatilla decoction (PD) and Si Junzi decoction, is efficacy to …