[PDF][PDF] Mechanisms modulating skeletal muscle phenotype

B Blaauw, S Schiaffino, C Reggiani - Compr Physiol, 2013 - researchgate.net
Mammalian skeletal muscles are composed of a variety of highly specialized fibers whose
selective recruitment allows muscles to fulfill their diverse functional tasks. In addition …

The muscle fiber type–fiber size paradox: hypertrophy or oxidative metabolism?

T Van Wessel, A De Haan, WJ Van Der Laarse… - European journal of …, 2010 - Springer
An inverse relationship exists between striated muscle fiber size and its oxidative capacity.
This relationship implies that muscle fibers, which are triggered to simultaneously increase …

The myokine decorin is regulated by contraction and involved in muscle hypertrophy

T Kanzleiter, M Rath, SW Görgens, J Jensen… - Biochemical and …, 2014 - Elsevier
The health-promoting effects of regular exercise are well known, and myokines may mediate
some of these effects. The small leucine-rich proteoglycan decorin has been described as a …

Low-intensity resistance training attenuates dexamethasone-induced atrophy in the flexor hallucis longus muscle

AG Macedo, ALO Krug, NA Herrera, AS Zago… - The Journal of steroid …, 2014 - Elsevier
This study investigated the potential protective effect of low-intensity resistance training (RT)
against dexamethasone (DEX) treatment induced muscle atrophy. Rats underwent either an …

Effects of exercise training on glucocorticoid-induced muscle atrophy: literature review

AG Macedo, TAF Almeida, DA Massini, VF De Paula… - Steroids, 2023 - Elsevier
Glucocorticoids (GCs) administration, such as cortisol acetate (CA) and dexamethasone
(DEXA), is used worldwide due to their anti-inflammatory, anti-allergic, and …

[PDF][PDF] Sarcopenia: monitoring, molecular mechanisms, and physical intervention.

A Zembroń-Łacny, W Dziubek… - Physiological …, 2014 - pdfs.semanticscholar.org
Summary According to European Working Group on Sarcopenia in Older People (EWGSOP)
sarcopenia includes both a loss of muscle strength and a decline in functional quality in …

The effects of acute and chronic exercise on the vasculature

JJ Whyte, M Harold Laughlin - Acta physiologica, 2010 - Wiley Online Library
Regular physical activity (endurance training, ET) has a strong positive link with
cardiovascular health. The aim of this review is to draw together the current knowledge on …

Muscle hypertrophy is associated with increases in proteasome activity that is independent of MuRF1 and MAFbx expression

LM Baehr, M Tunzi, SC Bodine - Frontiers in physiology, 2014 - frontiersin.org
The regulation of skeletal muscle mass depends on the balance between protein synthesis
and degradation. The role of protein degradation and in particular, the ubiquitin proteasome …

Targeting inflammation and downstream protein metabolism in sarcopenia: a brief up-dated description of concurrent exercise and leucine-based multimodal …

Z Xia, J Cholewa, Y Zhao, HY Shang, YQ Yang… - Frontiers in …, 2017 - frontiersin.org
Sarcopenia is defined as the progressive loss of muscle mass with age, and poses a serious
threat to the physiological and psychological health of the elderly population with …

Molecular mechanisms of exercise and healthspan

Y Guan, Z Yan - Cells, 2022 - mdpi.com
Healthspan is the period of our life without major debilitating diseases. In the modern world
where unhealthy lifestyle choices and chronic diseases taper the healthspan, which lead to …