The microbiome and inflammatory bowel disease
KL Glassner, BP Abraham, EMM Quigley - Journal of Allergy and Clinical …, 2020 - Elsevier
Inflammatory bowel disease (IBD) is a chronic immune-mediated disease affecting the
gastrointestinal tract. IBD consists of 2 subtypes: ulcerative colitis and Crohn disease. IBD is …
gastrointestinal tract. IBD consists of 2 subtypes: ulcerative colitis and Crohn disease. IBD is …
Recent advances in anti-virulence therapeutic strategies with a focus on dismantling bacterial membrane microdomains, toxin neutralization, quorum-sensing …
O Fleitas Martínez, MH Cardoso, SM Ribeiro… - Frontiers in cellular …, 2019 - frontiersin.org
Antimicrobial resistance constitutes one of the major challenges facing humanity in the
Twenty-First century. The spread of resistant pathogens has been such that the possibility of …
Twenty-First century. The spread of resistant pathogens has been such that the possibility of …
Construction and analysis of two genome-scale deletion libraries for Bacillus subtilis
A systems-level understanding of Gram-positive bacteria is important from both an
environmental and health perspective and is most easily obtained when high-quality …
environmental and health perspective and is most easily obtained when high-quality …
Thousands of previously unknown phages discovered in whole-community human gut metagenomes
Background Double-stranded DNA bacteriophages (dsDNA phages) play pivotal roles in
structuring human gut microbiomes; yet, the gut virome is far from being fully characterized …
structuring human gut microbiomes; yet, the gut virome is far from being fully characterized …
Functional signatures of oral dysbiosis during periodontitis progression revealed by microbial metatranscriptome analysis
Background Periodontitis is a polymicrobial biofilm-induced inflammatory disease that
affects 743 million people worldwide. The current model to explain periodontitis progression …
affects 743 million people worldwide. The current model to explain periodontitis progression …
Membrane microdomain disassembly inhibits MRSA antibiotic resistance
E García-Fernández, G Koch, RM Wagner, A Fekete… - Cell, 2017 - cell.com
A number of bacterial cell processes are confined functional membrane microdomains
(FMMs), structurally and functionally similar to lipid rafts of eukaryotic cells. How bacteria …
(FMMs), structurally and functionally similar to lipid rafts of eukaryotic cells. How bacteria …
Understanding human glycosylation disorders: biochemistry leads the charge
HH Freeze - Journal of Biological Chemistry, 2013 - ASBMB
Nearly 70 inherited human glycosylation disorders span a breathtaking clinical spectrum,
impacting nearly every organ system and launching a family-driven diagnostic odyssey …
impacting nearly every organ system and launching a family-driven diagnostic odyssey …
MAIT and Vδ2 unconventional T cells are supported by a diverse intestinal microbiome and correlate with favorable patient outcome after allogeneic HCT
H Andrlová, O Miltiadous, AI Kousa, A Dai… - Science translational …, 2022 - science.org
Microbial diversity is associated with improved outcomes in recipients of allogeneic
hematopoietic cell transplantation (allo-HCT), but the mechanism underlying this …
hematopoietic cell transplantation (allo-HCT), but the mechanism underlying this …
[HTML][HTML] BTN2A1, an immune checkpoint targeting Vγ9Vδ2 T cell cytotoxicity against malignant cells
CE Cano, C Pasero, A De Gassart, C Kerneur… - Cell Reports, 2021 - cell.com
The anti-tumor response of Vγ9Vδ2 T cells requires the sensing of accumulated
phosphoantigens (pAgs) bound intracellularly to butyrophilin 3A1 (BTN3A1). In this study …
phosphoantigens (pAgs) bound intracellularly to butyrophilin 3A1 (BTN3A1). In this study …
Genome‐wide analyses of Liberibacter species provides insights into evolution, phylogenetic relationships, and virulence factors
SP Thapa, A De Francesco, J Trinh… - Molecular plant …, 2020 - Wiley Online Library
Abstract 'Candidatus Liberibacter'species are insect‐transmitted, phloem‐limited α‐
Proteobacteria in the order of Rhizobiales. The citrus industry is facing significant challenges …
Proteobacteria in the order of Rhizobiales. The citrus industry is facing significant challenges …