The human hippocampal formation is relevant for various aspects of memory and learning,
and the different hippocampal regions are differentially affected by neuropsychiatric …

Hippocampus serves as a pivotal role in cognitive and emotional processes, as well as in
the regulation of the hypothalamus-pituitary axis. It is known to undergo mild …

Epilepsy is a common neurological disorder affecting over 70 million people worldwide, with
a high rate of pharmaco-resistance, diverse comorbidities including progressive cognitive …

Several lines of evidence link deficient serotonin function and SUDEP. Chronic treatment
with serotonin reuptake inhibitors (SRIs) reduces ictal central apnoea, a risk factor for …

The CA2 pyramidal cells are mostly resistant to cell death in mesial temporal lobe epilepsy
(MTLE) with hippocampal sclerosis, but they are aberrantly integrated into the epileptic …

Temporal lobe epilepsy (TLE) is the most common form of intractable epilepsy where
hyperactive glutamate receptors may contribute to the complex epileptogenic network hubs …

The relationship between clinically accessible epileptic biomarkers and neuronal activity
underlying the transition to seizure is complex, potentially leading to imprecise delineation of …

Objective Despite decades of epilepsy research, 30% of focal epilepsies remain resistant to
antiseizure drugs, with effective drug development impeded by lack of understanding on …

Key points Local neocortical and hippocampal territories show different and sterotypical
patterns of acutely evolving, epileptiform activity. Neocortical and entorhinal networks show …

Quantitative electroencephalogram analysis has been increasingly applied to study fine
changes in brain oscillations in epilepsy. Here we aimed to evaluate interictal oscillations …