Nanoparticles‐induced potential toxicity on human health: applications, toxicity mechanisms, and evaluation models

L Xuan, Z Ju, M Skonieczna, PK Zhou, R Huang - MedComm, 2023 - Wiley Online Library
Nanoparticles (NPs) have become one of the most popular objects of scientific study during
the past decades. However, despite wealth of study reports, still there is a gap, particularly in …

[HTML][HTML] Advanced optical imaging for the rational design of nanomedicines

A Ortiz-Pérez, M Zhang, LW Fitzpatrick… - Advanced Drug Delivery …, 2023 - Elsevier
Despite the enormous potential of nanomedicines to shape the future of medicine, their
clinical translation remains suboptimal. Translational challenges are present in every step of …

[HTML][HTML] Immunotoxic, genotoxic, and endocrine disrupting impacts of polyamide microplastic particles and chemicals

A Alijagic, O Kotlyar, M Larsson, S Salihovic… - Environment …, 2024 - Elsevier
Due to their exceptional properties and cost effectiveness, polyamides or nylons have
emerged as widely used materials, revolutionizing diverse industries, including industrial 3D …

NLRP3 inflammasome as a sensor of micro-and nanoplastics immunotoxicity

A Alijagic, A Hedbrant, A Persson, M Larsson… - Frontiers in …, 2023 - frontiersin.org
Micro-and nanoplastics (MNPs) are emerging pollutants with scarcely investigated effects on
human innate immunity. If they follow a similar course of action as other, more thoroughly …

Health hazards of particles in additive manufacturing: a cross-disciplinary study on reactivity, toxicity and occupational exposure to two nickel-based alloys

HL Karlsson, NVS Vallabani, X Wang, M Assenhöj… - Scientific Reports, 2023 - nature.com
The increasing use of additive manufacturing (AM) techniques (eg, 3D-printing) offers many
advantages but at the same time presents some challenges. One concern is the possible …

[HTML][HTML] Metabolic and phenotypic changes induced by PFAS exposure in two human hepatocyte cell models

A Alijagic, L Sinisalu, D Duberg, O Kotlyar… - Environment …, 2024 - Elsevier
PFAS are ubiquitous industrial chemicals with known adverse health effects, particularly on
the liver. The liver, being a vital metabolic organ, is susceptible to PFAS-induced metabolic …

Assessing biologic/toxicologic effects of extractables from plastic contact materials for advanced therapy manufacturing using cell painting assay and cytotoxicity …

I Pahl, A Pahl, A Hauk, D Budde, S Sievers, L Fruth… - Scientific Reports, 2024 - nature.com
Plastic components are essential in the pharmaceutical industry, encompassing container
closure systems, laboratory handling equipment, and single-use systems. As part of their …

[HTML][HTML] The triple exposure nexus of microplastic particles, plastic-associated chemicals, and environmental pollutants from a human health perspective

A Alijagic, D Suljević, M Fočak, J Sulejmanović… - Environment …, 2024 - Elsevier
The presence of microplastics (MPs) is increasing at a dramatic rate globally, posing risks for
exposure and subsequent potential adverse effects on human health. Apart from being …

[HTML][HTML] Cocktail effects of tire wear particles leachates on diverse biological models: A multilevel analysis

J Le Du-Carrée, CK Palacios, A Rotander… - Journal of Hazardous …, 2024 - Elsevier
Tire wear particles (TWP) stand out as a major contributor to microplastic pollution, yet their
environmental impact remains inadequately understood. This study delves into the cocktail …

Characteristics and health risks of the inhalable fraction of metal additive manufacturing powders

A Alijagic, X Wang, NVS Vallabani, P Melin… - Nano …, 2024 - Wiley Online Library
Metal additive manufacturing (AM) is gaining traction but raises worker health concerns due
to micron‐sized powders, including fine inhalable particles. This study explored particle and …