Prevention, treatment and cure of HIV infection

RJ Landovitz, H Scott, SG Deeks - Nature Reviews Microbiology, 2023 - nature.com
The development of antiretroviral therapy for the prevention and treatment of HIV infection
has been marked by a series of remarkable successes. However, the efforts to develop a …

Important considerations regarding the widespread use of doxycycline chemoprophylaxis against sexually transmitted infections

FYS Kong, C Kenyon, M Unemo - Journal of Antimicrobial …, 2023 - academic.oup.com
Rates of sexually transmitted infections (STIs) continue to rise across the world and
interventions are essential to reduce their incidence. Past and recent studies have indicated …

Mpox and HIV: a narrative review

CS Saldana, CF Kelley, BM Aldred… - Current HIV/AIDS Reports, 2023 - Springer
Abstract Purpose of Review We reviewed the available literature on mpox in People with
HIV (PWH). We highlight special considerations of mpox infection related to epidemiology …

In vivo HIV dynamics, modeling the interaction of HIV and immune system via non-integer derivatives

A Jan, HM Srivastava, A Khan, PO Mohammed… - Fractal and …, 2023 - mdpi.com
The economic burden of HIV extends beyond the individual level and affects communities
and countries. HIV can lead to decreased economic growth due to lost productivity and …

Impact of integrase inhibitors on cardiovascular disease events in people with human immunodeficiency virus starting antiretroviral therapy

B Surial, F Chammartin, J Damas… - Clinical Infectious …, 2023 - academic.oup.com
Background Integrase strand transfer inhibitors (INSTIs) have been associated with an
increased risk for cardiovascular disease (CVD) events. We investigated the impact of …

Virological failure after switch to long-acting cabotegravir and rilpivirine injectable therapy: an in-depth analysis

BJ van Welzen, SFL Van Lelyveld… - Clinical Infectious …, 2024 - academic.oup.com
Background Long-acting (LA) injectable therapy with cabotegravir (CAB) and rilpivirine
(RPV) is currently used as maintenance treatment for human immunodeficiency virus type 1 …

Prevention strategies for sexually transmitted infections, HIV, and viral hepatitis in Europe

D Gökengin, T Noori, A Alemany… - The Lancet Regional …, 2023 - thelancet.com
The current prevention efforts for STIs, HIV and viral hepatitis in the WHO European Region,
especially in the Central and Eastern subregions, are hindered by healthcare disparities …

Implementation and outcomes of dolutegravir-based first-line antiretroviral therapy for people with HIV in South Africa: a retrospective cohort study

J Dorward, Y Sookrajh, T Khubone, J van der Molen… - The Lancet …, 2023 - thelancet.com
Background There are few data assessing the uptake of first-line dolutegravir among men
and women living with HIV in low-income and middle-income countries, and subsequent …

Treatment emergent dolutegravir resistance mutations in individuals naive to HIV-1 integrase inhibitors: a rapid scoping review

K Tao, SY Rhee, C Chu, A Avalos, AK Ahluwalia… - Viruses, 2023 - mdpi.com
Background: Dolutegravir (DTG)-based antiretroviral therapy (ART) rarely leads to
virological failure (VF) and drug resistance in integrase strand transfer inhibitor (INSTI)-naïve …

Weight gain after HIV therapy initiation: pathophysiology and implications

NC Chandiwana, MJ Siedner… - The Journal of …, 2024 - academic.oup.com
Rapid advances in the potency, safety, and availability of modern HIV antiretroviral therapy
(ART) have yielded a near-normal life expectancy for most people living with HIV (PLWH) …