Brain-derived neurotrophic factor in Alzheimer's disease and its pharmaceutical potential

L Gao, Y Zhang, K Sterling, W Song - Translational neurodegeneration, 2022 - Springer
Synaptic abnormalities are a cardinal feature of Alzheimer's disease (AD) that are known to
arise as the disease progresses. A growing body of evidence suggests that pathological …

New frontiers in neurodegeneration and regeneration associated with brain-derived neurotrophic factor and the rs6265 single nucleotide polymorphism

CA Szarowicz, K Steece-Collier… - International journal of …, 2022 - mdpi.com
Brain-derived neurotrophic factor is an extensively studied neurotrophin implicated in the
pathology of multiple neurodegenerative and psychiatric disorders including, but not limited …

Cerebrospinal fluid biomarkers in patients with unipolar depression compared with healthy control individuals: a systematic review and meta-analysis

IV Mousten, NV Sørensen, RHB Christensen… - JAMA …, 2022 - jamanetwork.com
Importance Depression has been associated with alterations in neurotransmitters,
hormones, and inflammatory and neurodegenerative biomarkers, and biomarkers quantified …

BDNF and pro-BDNF in serum and exosomes in major depression: Evolution after antidepressant treatment

T Gelle, RA Samey, B Plansont, B Bessette… - Progress in Neuro …, 2021 - Elsevier
Background The study of clinically related biological indicators in Major Depression (MD) is
important. The Brain Derived Neurotrophic Factor (BDNF) appears to play an important role …

Depression and lifestyle: focusing on nutrition, exercise, and their possible relevance to molecular mechanisms

H Kunugi - Psychiatry and Clinical Neurosciences, 2023 - Wiley Online Library
Accumulating evidence has suggested the important role of lifestyle factors in depressive
disorder. This paper aimed to introduce and outline recent research on epidemiological and …

Cerebrospinal fluid and blood biomarkers of neuroinflammation and blood-brain barrier in psychotic disorders and individually matched healthy controls

R Jeppesen, S Orlovska-Waast… - Schizophrenia …, 2022 - academic.oup.com
Abstract Background and Hypothesis Neuroinflammation and blood-brain barrier (BBB)
dysfunction have been observed in patients with psychotic disorders. However, previous …

Iron, neuro‐bioavailability and depression

C Berthou, JP Iliou, D Barba - EJHaem, 2022 - Wiley Online Library
Medical management of iron deficiency (ID) requires to consider its consequences in
biochemical and physiological plural functions, beyond heme/hemoglobin disrupted …

Lower brain-derived neurotrophic factor levels are associated with age-related memory impairment in community-dwelling older adults: the Sefuri study

Y Mizoguchi, H Yao, Y Imamura, M Hashimoto… - Scientific Reports, 2020 - nature.com
The beneficial effects of brain-derived neurotrophic factor (BDNF)—a member of the
neurotrophin family—on cognitive function or dementia are well established in both rodents …

[HTML][HTML] Gut microbiota and pathophysiology of depressive disorder

H Kunugi - Annals of Nutrition and Metabolism, 2021 - karger.com
Background: Accumulating evidence has suggested that the bi-directional communication
pathway, the microbiota-gut-brain axis, plays an important role in the pathophysiology of …

[HTML][HTML] Minocycline treatment prevents depression and anxiety-like behaviors and promotes neuroprotection after experimental ischemic stroke

QM Camargos, BC Silva, DG Silva… - Brain research …, 2020 - Elsevier
Depression and anxiety have been reported as the major neuropsychiatric consequences
following stroke. Minocycline, a neuroprotective drug has minimized depressive symptoms …