Sex hormones, sleep, and memory: interrelationships across the adult female lifespan
YA Harrington, JM Parisi, D Duan… - Frontiers in Aging …, 2022 - frontiersin.org
As the population of older adults grows, so will the prevalence of aging-related conditions,
including memory impairments and sleep disturbances, both of which are more common …
including memory impairments and sleep disturbances, both of which are more common …
Magnetic resonance imaging Locus Coeruleus abnormality in amnestic Mild Cognitive Impairment is associated with future progression to dementia
Background and purpose Human neuropathological studies indicate that the pontine
nucleus Locus Coeruleus (LC) undergoes significant and early degeneration in Alzheimer's …
nucleus Locus Coeruleus (LC) undergoes significant and early degeneration in Alzheimer's …
Associations between locus coeruleus integrity and nocturnal awakenings in the context of Alzheimer's disease plasma biomarkers: a 7T MRI study
M Van Egroo, RWE van Hooren, HIL Jacobs - Alzheimer's research & …, 2021 - Springer
Background The brainstem locus coeruleus (LC) constitutes the intersection of the initial
pathophysiological processes of Alzheimer's disease (AD) and sleep-wake dysregulation in …
pathophysiological processes of Alzheimer's disease (AD) and sleep-wake dysregulation in …
Functional locus coeruleus imaging to investigate an ageing noradrenergic system
M Ludwig, YJ Yi, F Lüsebrink, MF Callaghan… - Communications …, 2024 - nature.com
The locus coeruleus (LC), our main source of norepinephrine (NE) in the brain, declines with
age and is a potential epicentre of protein pathologies in neurodegenerative diseases (ND) …
age and is a potential epicentre of protein pathologies in neurodegenerative diseases (ND) …
Different patterns of locus coeruleus MRI alteration in Alzheimer's and dementia with Lewy bodies
Background: The integrity of Locus Coeruleus can be evaluated in vivo using specific
Magnetic Resonance Imaging sequences. While this nucleus has been shown to be …
Magnetic Resonance Imaging sequences. While this nucleus has been shown to be …
Daily heart rate variability biofeedback training decreases locus coeruleus MRI contrast in younger adults in a randomized clinical trial
As an arousal hub region in the brain, the locus coeruleus (LC) has bidirectional
connections with the autonomic nervous system. Magnetic resonance imaging (MRI)-based …
connections with the autonomic nervous system. Magnetic resonance imaging (MRI)-based …
Associations between MRI-assessed locus coeruleus integrity and cortical gray matter microstructure
JA Elman, OK Puckett, DJ Hagler Jr, RC Pearce… - Cerebral …, 2022 - academic.oup.com
The locus coeruleus (LC) is one of the earliest sites of tau pathology, making it a key
structure in early Alzheimer's disease (AD) progression. As the primary source of …
structure in early Alzheimer's disease (AD) progression. As the primary source of …
Sex-Related Disparities in the Resting State Functional Connectivity of the Locus Coeruelus and Salience Network in Preclinical Alzheimer's Disease
Recent studies have demonstrated the pivotal role of locus coeruleus (LC) and salience
network (SN) resting state functional connectivity (rsFC) changes in the early stage of …
network (SN) resting state functional connectivity (rsFC) changes in the early stage of …
Invited Perspective: Blue Skies and Alzheimer's Disease
C Linnman - Environmental Health Perspectives, 2024 - ehp.niehs.nih.gov
brainstem, hippocampus, and striatum. 12–14 Once there, particles may induce microglial
activation, 15 tau phosphorylation, 16 and neuronal death. 17 The LC innervates the …
activation, 15 tau phosphorylation, 16 and neuronal death. 17 The LC innervates the …
[HTML][HTML] Eye movements reveal age differences in how arousal modulates saliency priority but not attention processing speed
The arousal-biased competition theory posits that inducing arousal increases attentional
priority of salient stimuli while reducing priority of non-pertinent stimuli. However, unlike in …
priority of salient stimuli while reducing priority of non-pertinent stimuli. However, unlike in …