Understanding the diversity of dynamic structures and functions of DNA and RNA in biology
requires tools that can selectively and intimately probe these biomolecules. Synthetic …

Fluorescence spectroscopy, one of the most informative and sensitive analytical techniques,
has played and continues to play key roles in modern research. Indeed, unraveling the inner …

Although there are some proposed explanations for aggregation-induced emission, a
phenomenon with applications that range from biosensors to organic light-emitting diodes …

The use of fluorescent nucleic acid base analogues is becoming increasingly important in
the fields of biology, biochemistry and biophysical chemistry as well as in the field of DNA …

Fluorescence labeling and probing are fundamental techniques for nucleic acid analysis
and quantification. However, new fluorescent probes and approaches are urgently needed …

A fluorescent ribonucleoside alphabet consisting of highly emissive purine (th A, th G) and
pyrimidine (th U, th C) analogues, all derived from thieno [3, 4-d] pyrimidine as the …

Base‐modified fluorescent nucleoside analog probes have been very valuable in the study
of nucleic acid structure and function. Many of them structurally resemble natural bases, and …

Conspectus In 1960, Weber prophesied that “There are many ways in which the properties
of the excited state can be utilized to study points of ignorance of the structure and function …

Direct radical addition reactions at the C 8-site of 2′-deoxyguanosine (dG) can afford C 8-
Ar-dG adducts that are produced by carcinogenic arylhydrazines, polycyclic aromatic …

Ionized nucleobases participate in pairing interactions outside of Watson and Crick's rules.
Base pairing and ionization can be coupled via global conformational changes to raise the …