The etiological agent of plague, Yersinia pestis, is most commonly transmitted by the bite of
infectious fleas. To date, at least 28 flea species occurring in North America have been …

Skin is an immunologically active tissue composed of specialized cells and agents that
capture and process antigens to confer immune protection. Transcutaneous immunization …

A richly told story of the collision between nature's smallest organism and history's mightiest
empire The Emperor Justinian reunified Rome's fractured empire by defeating the Goths and …

Yersinia pestis, the bacterial agent of plague, is enzootic in many parts of the world within
wild rodent populations and is transmitted by different flea vectors. The ecology of plague is …

Yersinia pestis is the causative agent of plague, a disease that can manifest as either
bubonic or pneumonic plague. An interesting feature of plague is that it is a rapidly …

Yersinia pestis, the plague bacillus, has an exceptional pathogenicity but the factors
responsible for its extreme virulence are still unknown. A genome comparison with its less …

Plague is a zoonosis transmitted by fleas and caused by the gram-negative bacterium
Yersinia pestis. During infection, the plasmidic caf1M1A1 operon that encodes the Y. pestis …

Arising from: J. Mecsas et al. Nature 427, 606 (2004) Mecsas and colleagues suggest that a
deficiency in the chemokine receptor CCR5 in humans is unlikely to confer protection …

Abstract Models occupy an essential position in the study of infectious disease as a result of
the ethical problems of exposing humans to potentially lethal agents. Deliberately induced …

In this study, we compare four different adjuvants, LT (R192G), CpG ODN, MPL® TDM, and
alum, for their ability to affect the magnitude, distribution, and duration of antibody responses …