Albumin has shown remarkable promise as a natural drug carrier by improving
pharmacokinetic (PK) profiles of anticancer drugs for tumor-targeted delivery. The …

Abstract Recently, Poly (lactic-co-glycolic) Acid (PLGA) has garnered great attention as
foundational material for biomedical applications due to inherent biocompatibility, and …

Although several nanomedicines got clinical approval over the past two decades, the clinical
translation rate is relatively small so far. There are many post-surveillance withdrawals of …

Over the last 30 years, diverse types of nano-sized drug delivery systems (nanoDDSs) have
been intensively explored for cancer therapy, exploiting their passive tumor targetability with …

Various immunotherapeutic agents that can elicit antitumor immune responses have
recently been developed with the potential for improved efficacy in treating cancer. However …

This work reports the development of a biomimetic membrane-wrapped nanoparticle
(MWNP) platform for targeted chemotherapy of acute myeloid leukemia (AML). Doxorubicin …

Mathematical models are used to characterize and optimize drug release in drug delivery
systems (DDS). One of the most widely used DDS is the poly (lactic-co-glycolic acid)(PLGA) …

Lung cancer is one of the deadliest pulmonary diseases in the world. Although docetaxel
(DTX) has exhibited superior efficacy in lung cancer treatment, it has demonstrated …

The systemic delivery of doxorubicin (DOX) to treat osteosarcoma requires an adequate
drug concentration to be effective, but in doing so, it raises the risk of increasing organ off …

Background Active targeting by surface-modified nanoplatforms enables a more precise and
elevated accumulation of nanoparticles within the tumor, thereby enhancing drug delivery …