Visual impairment intracranial pressure (VIIP) syndrome is considered an unexplained
major risk for future long-duration spaceflight. NASA recently redefined this syndrome as …

Two principal theories for the pathogenesis of glaucomatous optic neuropathy (GON) have
been described—a mechanical and a vascular theory. Both have been defended by various …

We propose here a conceptual framework for understanding the optic nerve head (ONH) as
a biomechanical structure. Basic principles of biomechanical engineering are used to …

Optical coherence tomography angiography (OCTA) is a relatively new, noninvasive, dye-
free imaging modality that provides a qualitative and quantitative assessment of the …

purpose. To test the hypothesis that pathophysiologic deformation of the lamina cribrosa and
anterior scleral canal wall underlies the onset of confocal scanning laser tomography …

Biomechanical factors acting at the level of the lamina cribrosa (LC) are postulated to play a
role in retinal ganglion cell dysfunction and loss in glaucoma. In support of this postulate, we …

Background: Open Angle Glaucoma (POAG) is the leading causes of irreversible blindness
worldwide. Elevated intraocular pressure is considered an important risk factor for …

purpose. To study the relationship between intraocular pressure (IOP) and the IOP-related
stress (force/cross-sectional area) it generates within the load-bearing connective tissues of …

▪ Abstract The eye transduces light, and we usually do not think of it as a biomechanical
structure. Yet it is actually a pressurized, thick-walled shell that has an internal and external …

Glaucoma is a neurodegenerative disease of the visual system and leading cause of
blindness worldwide. The disease is associated with sensitivity to intraocular pressure (IOP) …