Catalytic Reactions and Energy Conservation in the Cytochrome bc1 and b6f Complexes of Energy-Transducing Membranes

M Sarewicz, S Pintscher, R Pietras, A Borek… - Chemical …, 2021 - ACS Publications
This review focuses on key components of respiratory and photosynthetic energy-
transduction systems: the cytochrome bc 1 and b 6 f (Cyt bc 1/b 6 f) membranous …

Mechanisms of energy transduction by charge translocating membrane proteins

F Calisto, FM Sousa, FV Sena, PN Refojo… - Chemical …, 2021 - ACS Publications
Life relies on the constant exchange of different forms of energy, ie, on energy transduction.
Therefore, organisms have evolved in a way to be able to harvest the energy made …

Delineating redox cooperativity in water‐soluble and membrane multiheme cytochromes through protein design

BJ Hardy, P Dubiel, EL Bungay, M Rudin… - Protein …, 2024 - Wiley Online Library
Nature has evolved diverse electron transport proteins and multiprotein assemblies
essential to the generation and transduction of biological energy. However, substantially …

Reply to “Comment on 'How a Formate Dehydrogenase Responds to Oxygen: Unexpected O2 Insensitivity of an Enzyme Harboring Tungstopterin, Selenocysteine …

CS Raman - ACS Catalysis, 2023 - ACS Publications
Buckel has commented that we did not demonstrate electron bifurcation (EB) in our recent
publication [Graham et al. ACS Catal. 2022, 12, 10449–10471]. As the person who …

How a Formate Dehydrogenase Responds to Oxygen: Unexpected O2 Insensitivity of an Enzyme Harboring Tungstopterin, Selenocysteine, and [4Fe–4S] Clusters

JE Graham, D Niks, GM Zane, Q Gui, K Hom… - ACS …, 2022 - ACS Publications
The reversible two-electron interconversion of formate and CO2 is catalyzed by both
nonmetallo-and metallo-formate dehydrogenases (FDHs). The latter group comprises …

[HTML][HTML] From low-to high-potential bioenergetic chains: Thermodynamic constraints of Q-cycle function

L Bergdoll, F Ten Brink, W Nitschke, D Picot… - … et Biophysica Acta (BBA …, 2016 - Elsevier
The electrochemical parameters of all cofactors in the supercomplex formed by the
Rieske/cytb complex and the SoxM/A-type O 2-reductase from the menaquinone-containing …

Unexpected Heme Redox Potential Values Implicate an Uphill Step in Cytochrome b6f

M Szwalec, Ł Bujnowicz, M Sarewicz… - The Journal of Physical …, 2022 - ACS Publications
Cytochromes bc, key enzymes of respiration and photosynthesis, contain a highly conserved
two-heme motif supporting cross-membrane electron transport (ET) that connects the two …

[HTML][HTML] ROS signaling capacity of cytochrome bc1: Opposing effects of adaptive and pathogenic mitochondrial mutations

J Pagacz, A Broniec, M Wolska, A Osyczka… - Free Radical Biology and …, 2021 - Elsevier
Cytochrome bc 1, also known as mitochondrial complex III, is considered to be one of the
important producers of reactive oxygen species (ROS) in living organisms. Under …

Dynamics of Lysine as a Heme Axial Ligand: NMR Analysis of the Chlamydomonas reinhardtii Hemoglobin THB1

MR Preimesberger, A Majumdar, JTJ Lecomte - Biochemistry, 2017 - ACS Publications
Nitrate metabolism in Chlamydomonas reinhardtii involves THB1, a monomeric hemoglobin
thought to function as a nitric oxide dioxygenase (NOD). NOD activity requires dioxygen and …

Hydrogen bonding rearrangement by a mitochondrial disease mutation in cytochrome bc1 perturbs heme bH redox potential and spin state

P Kuleta, J Lasham, M Sarewicz… - Proceedings of the …, 2021 - National Acad Sciences
Hemes are common elements of biological redox cofactor chains involved in rapid electron
transfer. While the redox properties of hemes and the stability of the spin state are …