International Union of Pharmacology. XXVII. Classification of cannabinoid receptors
AC Howlett, F Barth, TI Bonner, G Cabral… - Pharmacological …, 2002 - ASPET
Two types of cannabinoid receptor have been discovered so far, CB1 (2.1: CBD: 1: CB1:),
cloned in 1990, and CB2 (2.1: CBD: 2: CB2:), cloned in 1993. Distinction between these …
cloned in 1990, and CB2 (2.1: CBD: 2: CB2:), cloned in 1993. Distinction between these …
[图书][B] Pharmacological actions of cannabinoids
RG Pertwee - 2005 - Springer
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The cannabinoid receptor
AC Howlett, DM Evans, DB Houston - Marijuana/cannabinoids, 2019 - taylorfrancis.com
In the case of the cannabinoid receptor, the lack of potent antagonists has been a limiting
factor in defining cannabinoid receptor-mediated responses. Several lines of evidence …
factor in defining cannabinoid receptor-mediated responses. Several lines of evidence …
Cannabinoid receptors and pain
RG Pertwee - Progress in neurobiology, 2001 - Elsevier
Mammalian tissues contain at least two types of cannabinoid receptor, CB1 and CB2, both
coupled to G proteins. CB1 receptors are expressed mainly by neurones of the central and …
coupled to G proteins. CB1 receptors are expressed mainly by neurones of the central and …
Cannabinoid receptors and their ligands
RG Pertwee, RA Ross - … , Leukotrienes and Essential Fatty Acids (PLEFA), 2002 - Elsevier
There are at least two types of cannabinoid receptors, CB1 and CB2, both coupled to G
proteins. CB1 receptors exist primarily on central and peripheral neurons, one of their …
proteins. CB1 receptors exist primarily on central and peripheral neurons, one of their …
Cannabinoids and neuroinflammation
Growing evidence suggests that a major physiological function of the cannabinoid signaling
system is to modulate neuroinflammation. This review discusses the anti‐inflammatory …
system is to modulate neuroinflammation. This review discusses the anti‐inflammatory …
The endocannabinoid system: drug targets, lead compounds, and potential therapeutic applications
DM Lambert, CJ Fowler - Journal of medicinal chemistry, 2005 - ACS Publications
As far as can be ascertained from archeological sources, preparations of the hemp
Cannabis sativa L. were widely used by humans for either therapeutic or ritual purposes in …
Cannabis sativa L. were widely used by humans for either therapeutic or ritual purposes in …
'Entourage' effects of N‐palmitoylethanolamide and N‐oleoylethanolamide on vasorelaxation to anandamide occur through TRPV1 receptors
WSV Ho, DA Barrett, MD Randall - British journal of …, 2008 - Wiley Online Library
Background and purpose: The endocannabinoid N‐arachidonoylethanolamide
(anandamide) is co‐synthesized with other N‐acylethanolamides, namely N …
(anandamide) is co‐synthesized with other N‐acylethanolamides, namely N …
Cannabinoid receptors: nomenclature and pharmacological principles
The CB1 and CB2 cannabinoid receptors are members of the G protein-coupled receptor
(GPCR) family that are pharmacologically well defined. However, the discovery of additional …
(GPCR) family that are pharmacologically well defined. However, the discovery of additional …
Endogenous cannabinoids revisited: a biochemistry perspective
BM Fonseca, MA Costa, M Almada… - Prostaglandins & other …, 2013 - Elsevier
Marijuana is the most commonly used illegal drug, particularly in Western societies. The
discovery of an endogenous cannabinoid system (ECS) highlighted new molecules in …
discovery of an endogenous cannabinoid system (ECS) highlighted new molecules in …