From animal poisons and venoms to medicines: achievements, challenges and perspectives in drug discovery

KCF Bordon, CT Cologna, EC Fornari-Baldo… - Frontiers in …, 2020 - frontiersin.org
Animal poisons and venoms are comprised of different classes of molecules displaying wide-
ranging pharmacological activities. This review aims to provide an in-depth view of toxin …

Polymeric wound dressings, an insight into polysaccharide-based electrospun membranes

M Gruppuso, G Turco, E Marsich, D Porrelli - Applied Materials Today, 2021 - Elsevier
Chronic wounds deeply invalidate patient's quality of life, involving very high costs for the
medical system. Numerous wound dressings have been studied over the years, and active …

Venomous caterpillars: From inoculation apparatus to venom composition and envenomation

IM Villas-Boas, G Bonfa, DV Tambourgi - Toxicon, 2018 - Elsevier
Envenomation by the larval or pupal stages of moths occurs when the victim presses their
hairs. They penetrate the subcutaneous tissue, releasing toxins such as proteolytic …

Mechanisms involved in the cytoprotective effects of Lonomia obliqua venom on human endometrial stromal cells

R de Almeida Schneider, PB Terraciano, P Zanon… - Toxicon, 2024 - Elsevier
The pathophysiology of recurrent pregnancy loss (RPL) involves deficiencies in the
proliferation and migration capacities of endometrial stromal cells (hESCs), which impair …

Lonomia obliqua Envenoming and Innovative Research

MP Alvarez-Flores, RN Gomes, D Trevisan-Silva… - Toxins, 2021 - mdpi.com
As a tribute to Butantan Institute in its 120th anniversary, this review describes some of the
scientific research efforts carried out in the study of Lonomia envenoming in Brazil, a country …

Hemolin, an immunoglobulin-like peptide, opsonizes nonself targets for phagocytosis and encapsulation in Spodoptera exigua, a lepidopteran insect

J Jung, SM Sajjadian, Y Kim - Journal of Asia-Pacific Entomology, 2019 - Elsevier
Hemolin is an immunoglobulin-like peptide that plays crucial role in microbial pathogen
surveillance. However, its specific molecular actions in immune responses remain largely …

CmHem, a hemolin-like gene identified from Cnaphalocrocis medinalis, involved in metamorphosis and baculovirus infection

G Han, C Li, N Zhang, Q Liu, L Huang, Y Xia, J Xu - PeerJ, 2023 - peerj.com
Background As a member of the immunoglobulin superfamily, hemolins play a vital role in
insect development and defense against pathogens. However, the innate immune response …

Hydrogel films of methanolic Mentha piperita extract and silver nanoparticles enhance wound healing in rats with diabetes Type I

M Mojally, E Sharmin, Y Alhindi, NA Obaid… - Journal of Taibah …, 2022 - Taylor & Francis
Poor wound healing is considered an obstacle in diabetics, which requires effective therapy.
Our goal was to investigate the combined effect of mint and silver nanoparticle hydrogel …

Losac and Lopap Recombinant Proteins from Lonomia obliqua Bristles Positively Modulate the Myoblast Proliferation Process

AM Alvarez, MP Alvarez-Flores… - Frontiers in Molecular …, 2022 - frontiersin.org
The pursuit of better therapies for disorders creating deficiencies in skeletal muscle
regeneration is in progress, and several biotoxins are used in skeletal muscle research …

A systematic review of the bioprospecting potential of Lonomia spp. (Lepidoptera: Saturniidae)

HG Riva, AR Amarillo-S - Toxin Reviews, 2023 - Taylor & Francis
Toxins from venomous animals are proteins used for their defense or to hunt. Lonomia
(Lepidoptera: Saturniidae) caterpillars can be lethal, and accidental inoculation of the …