In pharmaceutical research and development, various new chemical entities (NCE) are
found to be poorly water-soluble. Therefore, solubility enhancement, a key factor for higher …

Nanosuspensions (NS), with their submicron particle sizes and unique physicochemical
properties, provide a versatile solution for enhancing the administration of medications that …

One challenge in the development of new drug formulations is overcoming their low
solubility in relevant aqueous media. Reducing the particle size of drug powders to a few …

We studied the application of pulsed laser ablation (PLA) for particle size reduction in non-
steroidal anti-inflammatory drugs (NSAIDs). Grinding of the poorly water-soluble NSAID …

Several disintegration procedures are well known in the field of pharmaceutical technology
to improve the solubility, dissolution rate and bioavailability. Only a few, organic materials …

Oil spills represent a critical environmental threat, particularly to marine ecosystems,
necessitating the development of efficient and eco-friendly remediation technologies. This …

The primary aim of our study is to formulate the meloxicam loaded chitosan-magnetite
nanoconjugates (MC-MNCs) for the magnetically targeted rheumatoid arthritis therapy with …

The increasing prevalence of water insoluble or poorly soluble drugs calls for the
development of new formulation methods. Common approaches include the reduction of …

In pharmaceutical development, more and more drugs are classified as poorly water-soluble
or insoluble. Particle size reduction is a common way to fight this trend by improving …

We investigated the application of pulsed laser ablation (PLA) for the production of magnetic
nanoparticles (MNPs)/drug nanocomposites. Magnetic drug delivery vehicles can provide a …