Noninvasive magnetic resonance imaging measures of glymphatic system activity

K Kamagata, Y Saito, C Andica… - Journal of Magnetic …, 2024 - Wiley Online Library
The comprehension of the glymphatic system, a postulated mechanism responsible for the
removal of interstitial solutes within the central nervous system (CNS), has witnessed …

The etiology and evolution of magnetic resonance imaging-visible perivascular spaces: Systematic review and meta-analysis

SV Okar, F Hu, RT Shinohara, ES Beck… - Frontiers in …, 2023 - frontiersin.org
Objectives Perivascular spaces have been involved in neuroinflammatory and
neurodegenerative diseases. Upon a certain size, these spaces can become visible on …

Choroid plexus and perivascular space enlargement in neuropsychiatric systemic lupus erythematosus

M Gueye, P Preziosa, GA Ramirez, EP Bozzolo… - Molecular …, 2024 - nature.com
Choroid plexus (CP) enlargement is proposed as a marker of neuroinflammation in immune-
mediated conditions. CP involvement has also been hypothesized in the immunopathology …

Glymphatic function plays a protective role in ageing-related cognitive decline

J Wang, Y Zhou, K Zhang, W Ran, X Zhu… - Age and …, 2023 - academic.oup.com
Objective The glymphatic pathway, characterised as a cerebral drainage system, influences
cognitive function in neurodegenerative diseases; however, evidence is limited in a normal …

Cross-Vendor Test-Retest Validation of Diffusion Tensor Image Analysis along the Perivascular Space (DTI-ALPS) for Evaluating Glymphatic System Function.

X Liu, G Barisano, X Shao, K Jann, J Ringman… - Aging and …, 2024 - escholarship.org
The diffusion tensor image analysis along the perivascular space (DTI-ALPS) method was
proposed to evaluate glymphatic system (GS) function. However, few studies have validated …

Interstitial fluidopathy of the central nervous system: an umbrella term for disorders with impaired neurofluid dynamics

T Taoka, R Ito, R Nakamichi, T Nakane… - … Resonance in Medical …, 2024 - jstage.jst.go.jp
Interest in interstitial fluid dynamics has increased since the proposal of the glymphatic
system hypothesis. Abnormal dynamics of the interstitial fluid have been pointed out to be an …

Glymphatic pathway in sporadic cerebral small vessel diseases: from bench to bedside

J Xu, Y Su, J Fu, Y Shen, Q Dong, X Cheng - Ageing Research Reviews, 2023 - Elsevier
Cerebral small vessel diseases (CSVD) consist of a group of diseases with high
heterogeneity induced by pathologies of intracranial small blood vessels. Endothelium …

Dynamic changes in glymphatic function in reversible cerebral vasoconstriction syndrome

CH Wu, Y Kuo, YH Ling, YF Wang, JL Fuh… - The Journal of …, 2024 - Springer
Background The pathophysiology of the reversible cerebral vasoconstriction syndrome
(RCVS) remains enigmatic and the role of glymphatics in RCVS pathophysiology has not …

Cognitive impairment is related to glymphatic system dysfunction in pediatric multiple sclerosis

M Margoni, E Pagani, A Meani, P Preziosa… - Annals of …, 2024 - Wiley Online Library
Objective The aim of this study was to investigate whether, compared to pediatric healthy
controls (HCs), the glymphatic system is impaired in pediatric multiple sclerosis (MS) …

[HTML][HTML] The relationship between inflammation, impaired glymphatic system, and neurodegenerative disorders: A vicious cycle

Y Cai, Z Yangqiqi, L Shuo, Y Ma, Q Jiang, Q Wen… - Neurobiology of …, 2024 - Elsevier
The term “glymphatic” emerged roughly a decade ago, marking a pivotal point in
neuroscience research. The glymphatic system, a glial-dependent perivascular network …