Diabetes is one of the fastest growing diseases worldwide, projected to affect 693 million
adults by 2045. Devastating macrovascular complications (cardiovascular disease) and …

Mendelian randomization refers to an analytic approach to assess the causality of an
observed association between a modifiable exposure or risk factor and a clinically relevant …

Key questions in COVID-19 are the duration and determinants of infectious virus shedding.
Here, we report that infectious virus shedding is detected by virus cultures in 23 of the 129 …

Background Although diabetic kidney disease demonstrates both familial clustering and
single nucleotide polymorphism heritability, the specific genetic factors influencing risk …

Diabetic kidney disease (DKD) is one of the most serious complications of both type 1
(T1DM) and type 2 diabetes mellitus (T2DM). Current guidelines recommend a personalized …

Type 2 diabetes results from a complex interaction between genetic and environmental
factors. Precision medicine for type 2 diabetes using genetic data is expected to predict the …

Differences between sexes contribute to variation in the levels of fasting glucose and insulin.
Epidemiological studies established a higher prevalence of impaired fasting glucose in men …

Diabetes is the leading cause of ESRD. Despite evidence for a substantial heritability of
diabetic kidney disease, efforts to identify genetic susceptibility variants have had limited …

Diabetic kidney disease (DKD) is the most common etiology of chronic kidney disease
(CKD) in the industrialized world and accounts for much of the excess mortality in patients …

Abstract Purpose of Review To provide an updated summary of discoveries made to date
resulting from genome-wide association study (GWAS) and sequencing studies, and to …