Abstract The “metabolic syndrome”(MetS) is a clustering of components that reflect
overnutrition, sedentary lifestyles, and resultant excess adiposity. The MetS includes the …

Metabolic syndrome comprises a cluster of cardiovascular risk factors (hypertension, altered
glucose metabolism, dyslipidemia, and abdominal obesity) that occur in obese children …

Muscle insulin resistance is a key feature of obesity and type 2 diabetes and is strongly
associated with increased intramyocellular lipid content and inflammation. However, the …

Chlorogenic acid (CGA) has been shown to stimulate glucose uptake in skeletal muscle
through the activation of AMPK. However, its effect on other metabolic pathways and …

Recent studies have demonstrated that fatty acids induce insulin resistance in skeletal
muscle by blocking insulin activation of insulin receptor substrate-1 (IRS-1)-associated …

Excessive energy intake and reduced energy expenditure drive the development of insulin
resistance and metabolic diseases such as obesity and type 2 diabetes mellitus. Metabolic …

Type 2 diabetes mellitus (T2DM) is characterized by insulin resistance in liver and muscle
and impaired insulin secretion. Considerable evidence also implicates deranged adipocyte …

Background: Resistin, a cysteine-rich polypeptide encoded by the RETN gene, which plays
an important role in many mechanisms in rodent studies, including lipid metabolism …

Background Skeletal muscle is mainly responsible for insulin‐stimulated glucose disposal.
Dysfunction in skeletal muscle metabolism especially during obesity contributes to the …

Plasma concentrations of amino acids are frequently elevated in insulin-resistant states, and
a protein-enriched diet can impair glucose metabolism. This study examined effects of short …