Exploring the relationship between anastasis and mitochondrial ROS-mediated ferroptosis in metastatic chemoresistant cancers: a call for investigation

Y Cao, C Lu, NM Beeraka, S Efetov, M Enikeev… - Frontiers in …, 2024 - frontiersin.org
Ferroptosis induces significant changes in mitochondrial morphology, including membrane
condensation, volume reduction, cristae alteration, and outer membrane rupture, affecting …

[HTML][HTML] Decoding tumor microenvironment: EMT modulation in breast cancer metastasis and therapeutic resistance, and implications of novel immune checkpoint …

J Yuan, L Yang, H Zhang, NM Beeraka, D Zhang… - Biomedicine & …, 2024 - Elsevier
Tumor microenvironment (TME) and epithelial-mesenchymal transition (EMT) play crucial
roles in the initiation and progression of tumors. TME is composed of various cell types, such …

Pyrimidine–triazole‐tethered tert‐butyl‐piperazine‐carboxylate suppresses breast cancer by targeting estrogen receptor signaling and β‐catenin activation

J Yuan, L Yang, Z Li, H Zhang, Q Wang, B Wang… - IUBMB …, 2024 - Wiley Online Library
Several chemotherapeutics against breast cancer are constrained by their adverse effects
and chemoresistance. The development of novel chemotherapeutics to target metastatic …

Amiloride reduces fructosamine-3-kinase expression to restore sunitinib sensitivity in renal cell carcinoma

Y Bai, Y You, D Chen, Y Chen, Z Yin, S Liao, B You… - iScience, 2024 - cell.com
The kidney is a vital organ responsible for water and sodium metabolism, while the primary
function of amiloride is to promote the excretion of water and sodium. We investigated …

β-Hydroxybutyrate and melatonin suppress maladaptive UPR, excessive autophagy and pyroptosis in Aβ 1–42 and LPS-Induced SH-SY5Y cells

MH Maleki, F Omidi, Z Javanshir, M Bagheri… - Molecular Biology …, 2024 - Springer
Background Alzheimer's disease is a neurological disease characterized by the build-up of
amyloid beta peptide (Aβ) and lipopolysaccharide (LPS), which causes synapse …

Machine Learning Prediction and Simulation of Drugs Targeting GSK-3β in Breast Cancer

G Munieswaran, NK Subramani… - Current Drug …, 2025 - benthamdirect.com
Introduction and Objective Breast cancer ranks as the second-most prevalent cause of death
among women worldwide, with particularly elevated mortality rates in India. Breast cancer's …

Scope of Theoretical Approaches Studying the Ligand-Nrf2

EO Madrigal-Santillán… - The Role of NRF2 …, 2024 - books.google.com
The nuclear factor erythroid 2-related factor 2 (Nrf2) is a protein transcrip-tional factor
considered as an emerging target for multiple biological processes. Its study could be useful …

[引用][C] Scope of Theoretical Approaches Studying the Ligand-Nrf2 Interactions

MA Soriano-Ursúa, AL Ocampo-Néstor, MN Rosalez… - 2024 - IntechOpen