Polycyclic polyprenylated acylphloroglucinols (PPAPs) are a class of hybrid natural products
sharing the mevalonate/methylerythritol phosphate and polyketide biosynthetic pathways …

Abstract Garcinia kola Heckel (Clusiaceae) is a tree indigenous to West and Central Africa.
All plant parts, but especially the seeds, are of value in local folklore medicine. Garcinia kola …

Biomimetic syntheses of three polycylic polyprenylated acylphloroglucinol natural products
isolated from Hypericum papuanum, ialibinone A, ialibinone B, and hyperguinone B, have …

We report a stereodivergent, asymmetric total synthesis of (−)‐clusianone in six steps from
commercial materials. We implement a challenging cationic cyclization forging a bond …

The aim of this review is to present a detailed account of all published synthetic approaches
toward the [3.3. 1] bridged bicyclic class of phloroglucinol natural products most famously …

We describe an alkylative dearomatization/acid-mediated adamantane annulation
sequence that allows facile access to type A polyprenylated acylphloroglucinol natural …

The highly stereoselective total synthesis of nemorosone via a new approach to the bicyclo
[3.3. 1] nonane-2, 4, 9-trione core which features intramolecular cyclopropanation of an α …

The previous assignment of the type C skeleton of polycyclic polyprenylated
acylphloroglucinols (PPAPs) was controversial and proved to be incorrect in this study. The …

A short total synthesis, guided by biosynthetic considerations, of racemic merochlorin B is
presented. The formation of its isomer, merochlorin A, was not observed under the …

The formal enantioselective total synthesis of nemorosone, garsubellin A, clusianone, and
hyperforin is described. The catalytic asymmetric intramolecular cyclopropanation (CAIMCP) …