Leishmaniases remain a major public health problem today despite the vast amount of
research conducted on Leishmania pathogens. The biological model is genetically and …

Although leishmaniases are endemic in 98 countries, they are still considered neglected
tropical diseases. Leishmaniases are characterized by the emergence of new virulent and …

Cryptococcosis is a multifaceted fungal infection with variable clinical presentation and
outcome. As in many infectious diseases, this variability is commonly assigned to host …

Visceral leishmaniasis (VL) caused by Leishmania donovani is a major parasitic disease
prevalent in endemic regions of Bihar in India. In the absence of good chemotherapeutic …

In this study, we tested 10 essential oils (EOs) extracted from 10 plants issued from Sned
region (Tunisia) to evaluate both their leishmanicidal effects against Leishmania major and …

Infection with protozoan parasites of the genus Leishmania leads to a wide variety of clinical
disease syndromes called leishmaniasis, or more appropriately the leishmaniases [1]. The …

Several approaches have been previously used to elucidate the genetic basis of
Leishmania virulence. In general, they were based on laboratory Leishmania clones …

Over the past few years, several reports of DNA vaccines against murine cutaneous
experimental leishmaniasis came out with promising but sometimes discordant results. The …

Macrophage phenotype plays a crucial role in the pathogenesis of Leishmanial infection.
Pro-inflammatory cytokines signals through the Janus kinase/signal transducer and activator …

Background Leishmania (L) are intracellular protozoan parasites that are able to survive and
replicate within the harsh and potentially hostile phagolysosomal environment of …