Macrophages are present in most human tissues and have very diverse functions. Activated
macrophages are usually divided into two phenotypes, M1 macrophages and M2 …

Macrophages are cells of the innate immunity constituting the mononuclear phagocyte
system and endowed with remarkable different roles essential for defense mechanisms …

The roles of tumor-associated macrophages (TAMs) and circulating monocytes in human
cancer are poorly understood. Here, we show that monocyte subpopulation distribution and …

Human immunodeficiency virus type 1 (HIV-1) eradication is prevented by the establishment
on infection of cellular HIV-1 reservoirs that are not fully characterized, especially in genital …

Pulmonary metastasis of breast cancer cells is promoted by a distinct population of
macrophages, metastasis-associated macrophages (MAMs), which originate from …

In people living with HIV (PLWH) who are failing or unable to access combination
antiretroviral therapy (cART), monocytes and macrophages are important drivers of …

Macrophages, found in circulating blood as well as integrated into several tissues and
organs throughout the body, represent an important first line of defense against disease and …

Apolipoprotein B editing complex 3 family members are cytidine deaminases that play
important roles in intrinsic responses to infection by retroviruses and have been implicated …

HIV-1 has evolved mechanisms to evade host cell immune responses and persist for lifelong
infection. Latent cellular reservoirs are responsible for this persistence of HIV-1 despite the …

The microRNA, miR-155 regulates both adaptive and innate immune responses. In viral
infections, miR-155 can affect both innate immunity (interferon response, natural killer cell …