Experiencing stressful events early in life is lamentably very common and widespread
across the globe. Despite the strong link between experiencing such stress and developing …

Background Depression risk increases during adolescent development, and individual
differences in neural sensitivity to peer feedback (rejection vs. acceptance) may be a key …

Anhedonia is a cardinal characteristic of depression which predicts worse treatment
outcome and is among the most common residual symptoms following treatment. Behavioral …

Reduced activation of the Research Domain Criteria (RDoC) positive valence systems
(PVS) is observed in high-risk (HR) children of depressed mothers and predictive of future …

Aim Familial history is associated with an increased risk for major depressive disorder
(MDD). Despite the increased risk, some members of the familial high-risk population remain …

Neural signatures of suicide risk likely reflect a combination of specific and non-specific
factors, and clarifying specific factors may facilitate development of novel treatments …

Background Stress exposure contributes to the onset, maintenance, and recurrence of major
depressive disorder (MDD) in adolescents. However, the precise stress facets (eg chronicity …

Background Elevated depressive symptoms in early childhood strongly predict depression
onset in youth. Nevertheless, little is known about the neural correlates of these symptoms …

Background Symptoms of obsessive-compulsive disorder (OCD) have been conceptualized
as manifestations of decision-making deficits. Patients with OCD exhibit impairment during …

Objective Understanding the development of adolescent reward responsiveness and
inhibitory control is important as they are implicated in key outcomes, such as depression …