B Moosmann, C Behl - Expert opinion on investigational drugs, 2002 - Taylor & Francis
Oxidative stress is a ubiquitously observed hallmark of neurodegenerative disorders. Neuronal cell dysfunction and cell death due to oxidative stress may causally contribute to …
MF Beal - Annals of Neurology: Official Journal of the American …, 2003 - Wiley Online Library
There is considerable evidence suggesting that mitochondrial dysfunction and oxidative damage may play a role in the pathogenesis of Parkinson's disease (PD). This possibility …
H Rauchova - Physiological research, 2021 - ncbi.nlm.nih.gov
Summary Coenzyme Q 10 (CoQ 10), a lipophilic substituted benzoquinone, is present in animal and plant cells. It is endogenously synthetized in every cell and involved in a variety …
A Storch, WH Jost, P Vieregge, J Spiegel… - Archives of …, 2007 - jamanetwork.com
Background Major hallmarks in the pathophysiology of Parkinson disease are cellular energy depletion and oxidative stress leading to cellular dysfunction and death. Coenzyme …
M Sanoobar, S Eghtesadi, A Azimi, M Khalili… - Nutritional …, 2015 - Taylor & Francis
Objectives Multiple sclerosis (MS) is an immune-mediated neurodegenerative disease of central nervous system and recent studies show that inflammatory processes are highly …
AJ Duncan, SJR Heales - Molecular aspects of medicine, 2005 - Elsevier
This article aims to give a broad overview of some of the potential targets for nitric oxide (NO) in the brain. The relevance of NO in both physiological and pathological scenarios is …
M Sohmiya, M Tanaka, NW Tak, M Yanagisawa… - Journal of the …, 2004 - Elsevier
Oxidative stress is suggested to play an important role in the pathogenesis of Parkinson's disease (PD). However, no elevation of plasma oxidative stress marker has been reported …
M Flint Beal - Free Radical Research, 2002 - Taylor & Francis
Coenzyme Q 10 (CoQ 10) is an essential cofactor of the electron transport gene as well as an important antioxidant, which is particularly effective within mitochondria. A number of …
Mitochondria are key cellular organelles that play crucial roles in the energy production and regulation of cellular metabolism. Accumulating evidence suggests that mitochondrial …