Aptamers are artificial nucleic acid ligands, specifically generated against certain targets,
such as amino acids, drugs, proteins or other molecules. In nature they exist as a nucleic …

Realization of the advantages of stable isotope labeling for proteomics has emerged
gradually. However, many stable isotope label approaches rely on labeling in vitro using …

Monoclonal antibodies that recognize specific antigens of interest are used as therapeutic
agents and as tools for biomedical research. Discovering a single monoclonal antibody …

We coin the term “smart aptamers” aptamers with predefined binding parameters (k on, k off,
K d) of aptamer− target interaction. Aptamers, in general, are oligonucleotides, which are …

We define multivalency to be the operation of multiple molecular recognition events of the
same kind occurring simultaneously between two entities (molecules, molecular aggregates …

Immobilization of proteins onto surfaces is of great importance in numerous applications,
including protein analysis, drug screening, and medical diagnostics, among others. The …

A novel amperometric biosensor for performing simultaneous electrochemical multianalyte
immunoassays is described. The sensor consisted of eight iridium oxide sensing electrodes …

Kinetic capillary electrophoresis (KCE) is defined as capillary electrophoresis of species that
interact during electrophoresis. KCE can serve as a conceptual platform for development of …

A fast, simple, sensitive, and low-cost method for electrochemical multianalyte immunoassay
was developed by combining newly designed electric field-driven incubation with a screen …

Different protein extraction methods have been developed for plant proteome analysis but
their compatibility with mass spectrometry has rarely been tested. We evaluated four protein …