The utility of cfDNA in TGCT patient management: a systematic review

J Krasic, L Skara, AK Bojanac… - Therapeutic …, 2022 - journals.sagepub.com
Background: Testicular germ cell tumors (TGCTs) are the most common young male
malignancy with a steadily rising incidence. Standard clinical practice is radical …

SIN3‐HDAC complex‐associated factor, a chromatin remodelling gene located in the 12p amplicon, is a potential germ cell tumour‐specific oncogene

YL Jhuang, CW Yang, YF Tseng, CL Hsu… - The Journal of …, 2022 - Wiley Online Library
A genetic hallmark of malignant germ cell tumours (GCTs) is isochromosome 12p, but
oncogenes located in 12p that are specifically expressed in GCT have not yet been …

Testicular Germ Cell Tumor Tissue Biomarker Analysis: A Comparison of Human Protein Atlas and Individual Testicular Germ Cell Tumor Component …

J Krasic, L Skara Abramovic, M Himelreich Peric… - Cells, 2023 - mdpi.com
The accurate management of testicular germ cell tumors (TGCTs) depends on identifying the
individual histological tumor components. Currently available data on protein expression in …

Histone methylation and acetylation in cancer: mechanism, progression, and targets

S Bu, T Ye, H Gao, H Song, Y Zhu - Oncologie, 2024 - degruyter.com
Along with the continuous development of chromatin immunoprecipitation sequencing and
its derivative technologies, as well as an increased understanding of epigenetic …

Targeting histone deacetylases in testicular germ cell tumours: an encouraging treatment approach for the future

NT Tavares, R Henrique, C Jerónimo… - The Journal of …, 2023 - Wiley Online Library
Epidrugs, specifically histone deacetylase inhibitors (HDACi), have been increasingly used
in preclinical studies for the treatment of testicular germ cell tumours (TGCTs). SINHCAF was …

Valproate targets mammalian gastrulation impairing neural tissue differentiation and development of the placental source in vitro

A Katušić-Bojanac, M Plazibat… - International journal of …, 2022 - mdpi.com
The teratogenic activity of valproate (VPA), an antiepileptic and an inhibitor of histone
deacetylase (HDACi), is dose-dependent in humans. Previous results showed that VPA …

Ekspresija gena DPPA3 u neseminomskim tumorima zametnih stanica testisa

M Gangur - 2023 - zir.nsk.hr
Sažetak Tumori testisa, poznati kao tumori zametnih stanica testisa (engl. testicular germ
cell tumors, TGCT), predstavljaju najučestalije neoplazme koje zahvaćaju muškarce u …

[PDF][PDF] Metilacija nestanične DNA gena RASSF1A i PRSS21 u krvi i ejakulatu bolesnika s neseminomskim tumorima zametnih stanica testisa

J Krasić - 2022 - repozitorij.mef.unizg.hr
Sjemenik (lat. testis) je muški parni spolni organ ovalnog oblika smještena unutar mošnje
(lat. scrotum), lociran iza penisa i ispred anusa. U testisu se proizvode muške spolne stanice …

Imunohistokemijska vizualizacija proteina SOX2, SOX17 i CALCA u tumoru zametnih stanica sjemenika čovjeka

M Malnar - 2022 - repozitorij.unizg.hr
Sažetak Tumori sjemenika su najčešći tumori koji pogađaju muškarce u najreproduktivnijoj
dobi od 15 do 45 godina. Tumori zametnih stanica sjemenika (engl. testicular germ cell …