Global colistin use: a review of the emergence of resistant Enterobacterales and the impact on their genetic basis

U Binsker, A Käsbohrer… - FEMS Microbiology …, 2022 - academic.oup.com
The dramatic global rise of MDR and XDR Enterobacterales in human medicine forced
clinicians to the reintroduction of colistin as last-resort drug. Meanwhile, colistin is used in …

Treatment for carbapenem-resistant Enterobacterales infections: recent advances and future directions

K Tompkins, D van Duin - European Journal of Clinical Microbiology & …, 2021 - Springer
Carbapenem-resistant Enterobacterales (CRE) are a growing threat to human health
worldwide. CRE often carry multiple resistance genes that limit treatment options and …

Metagenomic analysis of the abundance and composition of antibiotic resistance genes in hospital wastewater in Benin, Burkina Faso, and Finland

MA Markkanen, K Haukka, KMM Pärnänen… - Msphere, 2023 - Am Soc Microbiol
Antibiotic resistance is a global threat to human health, with the most severe effect in low-
and middle-income countries. We explored the presence of antibiotic resistance genes …

Review and analysis of the overlapping threats of carbapenem and polymyxin resistant E. coli and Klebsiella in Africa

DM Venne, DM Hartley, MD Malchione, M Koch… - … Resistance & Infection …, 2023 - Springer
Abstract Background Carbapenem-resistant Enterobacterales are among the most serious
antimicrobial resistance (AMR) threats. Emerging resistance to polymyxins raises the …

Polyclonal emergence of MDR Enterobacter cloacae complex isolates producing multiple extended spectrum beta-lactamases at Maputo Central Hospital …

J Sumbana, A Santona, M Fiamma, E Taviani… - … Lincei. Scienze Fisiche …, 2022 - Springer
Enterobacter spp. are important nosocomial pathogens responsible of a wide variety of
infections, mainly due to Extended Spectrum β-Lactamase (ESBL) producing isolates …

Acquisition of Enterobacterales carrying the colistin resistance gene mcr following travel to the tropics

E Rondinaud, O Clermont, M Petitjean… - Journal of Travel …, 2023 - academic.oup.com
Background Colistin is an antibiotic of last resort in the management of highly drug-resistant
Enterobacterales infections. Travel to some destinations presents a high risk of acquiring …

[HTML][HTML] Molecular Characterization of Carbapenem and Colistin Resistance in Klebsiella pneumoniae Isolates Obtained from Clinical Samples at a University …

R Rihane, A Hecini-Hannachi, C Bentchouala… - Microorganisms, 2024 - mdpi.com
The current study aimed to determine the molecular mechanisms of carbapenem and
colistin resistance among the clinical isolates of Klebsiella pneumoniae from hospitalized …

Whole-genome epidemiology and characterisation of mcr-1-encoding Escherichia coli in aquatic bird farms from the Pearl River Delta, China, 2019–2020

Y Pan, Z Zeng, H Niu, L Huang, J Hu, G Li… - International Journal of …, 2022 - Elsevier
Due to their unique breeding pattern, aquatic bird farms are increasingly considered as
hotspots in the development and spread of antimicrobial resistance. However …

[HTML][HTML] Nosocomial outbreak of colistin-resistant, carbapenemase-producing Klebsiella pneumoniae ST11 in a medical intensive care unit

X Chen, Z Jiang, R Chen, Z Zhu, Y Wu, Z Sun… - Journal of Global …, 2024 - Elsevier
Objectives Klebsiella pneumoniae is an important opportunistic Gram-negative pathogen.
This study describes an outbreak due to colistin-resistant and carbapenem-resistant …

Carbapenemase Production and Detection of Colistin‐Resistant Genes in Clinical Isolates of Escherichia Coli from the Ho Teaching Hospital, Ghana

JG Deku, KO Duedu, GE Kpene… - Canadian Journal of …, 2022 - Wiley Online Library
Background. Effective and successful treatment of infectious diseases is a significant gain in
clinical settings. However, resistance to antibiotics, especially the last‐resort medicines …