Machine learning methods to support personalized neuromusculoskeletal modelling

DJ Saxby, BA Killen, C Pizzolato, CP Carty… - … and Modeling in …, 2020 - Springer
Many biomedical, orthopaedic, and industrial applications are emerging that will benefit from
personalized neuromusculoskeletal models. Applications include refined diagnostics …

In silico-enhanced treatment and rehabilitation planning for patients with musculoskeletal disorders: can musculoskeletal modelling and dynamic simulations really …

BA Killen, A Falisse, F De Groote, I Jonkers - Applied Sciences, 2020 - mdpi.com
Over the past decades, the use of computational physics-based models representative of the
musculoskeletal (MSK) system has become increasingly popular in many fields of clinically …

Automated analysis of alignment in long-leg radiographs by using a fully automated support system based on artificial intelligence

J Schock, D Truhn, DB Abrar, D Merhof… - Radiology: Artificial …, 2020 - pubs.rsna.org
Purpose To develop and validate a deep learning–based method for automatic quantitative
analysis of lower-extremity alignment. Materials and Methods In this retrospective study …

Multi-level personalization of neuromusculoskeletal models to estimate physiologically plausible knee joint contact forces in children

G Davico, DG Lloyd, CP Carty, BA Killen… - … and modeling in …, 2022 - Springer
Neuromusculoskeletal models are a powerful tool to investigate the internal biomechanics of
an individual. However, commonly used neuromusculoskeletal models are generated via …

[HTML][HTML] Automatic generation of personalised skeletal models of the lower limb from three-dimensional bone geometries

L Modenese, JB Renault - Journal of Biomechanics, 2021 - Elsevier
The generation of personalised and patient-specific musculoskeletal models is currently a
cumbersome and time-consuming task that normally requires several processing hours and …

Automated creation and tuning of personalised muscle paths for OpenSim musculoskeletal models of the knee joint

BA Killen, S Brito da Luz, DG Lloyd… - … and Modeling in …, 2021 - Springer
Computational modelling is an invaluable tool for investigating features of human
locomotion and motor control which cannot be measured except through invasive …

[HTML][HTML] Reconstruction of the lower limb bones from digitised anatomical landmarks using statistical shape modelling

D Nolte, ST Ko, AMJ Bull, AE Kedgley - Gait & posture, 2020 - Elsevier
Background Bone shapes strongly influence force and moment predictions of kinematic and
musculoskeletal models used in motion analysis. The precise determination of joint …

Minimal medical imaging can accurately reconstruct geometric bone models for musculoskeletal models

EK Suwarganda, LE Diamond, DG Lloyd, TF Besier… - PloS one, 2019 - journals.plos.org
Accurate representation of subject-specific bone anatomy in lower-limb musculoskeletal
models is important for human movement analyses and simulations. Mathematical methods …

Best methods and data to reconstruct paediatric lower limb bones for musculoskeletal modelling

G Davico, C Pizzolato, BA Killen, M Barzan… - … and Modeling in …, 2020 - Springer
In biomechanical simulations, generic linearly scaled musculoskeletal anatomies are
commonly used to represent children, often neglecting or oversimplifying subject-specific …

Improving musculoskeletal model scaling using an anatomical atlas: the importance of gender and anthropometric similarity to quantify joint reaction forces

Z Ding, CK Tsang, D Nolte… - IEEE Transactions on …, 2019 - ieeexplore.ieee.org
Objective: The accuracy of a musculoskeletal model relies heavily on the implementation of
the underlying anatomical dataset. Linear scaling of a generic model, despite being time …